5 - Oxidation Of Sugar Carbonyl Addition Reaction And On The Synthesis Of D-ribose

AbstractIn this thesis, we rePort our work as tWo peds.The first is the Study on the additional reaction of carbonyl of 1,2-O-isoproPylidene- a -D-glucoboos-5-ulose. By using arom8tic aInines, seven.new amino-sugar derivatives were synthesized and a new carbonyltransformation reaction was found,in which carbony was moved to 6-carben.The isomeriZation of comPound 5 was also inveStigated.er""O4 4 RcrhL -- g4O,ng O:1 o. r O') oH ty-- Ohly5 tty WR=P-CHs,p-CH3O,etal.A novel rout fOr prePare pesudsugar(carbosugar) was developed by stUdyon the reaction ofnitromathane addition to 5-oxo-sugar derivative.Ofy --%virt Hde...ty ofy OH-. - -Ih the secOnd part, 1,2-O-isOProPyiden- a -boboose wasoteshed frOIn irglucose via Protection, okidation, degradaon and reduction.The tOtal yteld ofdss rOut is 7l.3%.lerrhe ix1hOH &-- ghcrr ThICHOl Heq-- l Q "tri /\fo& -- "VOH O~ \ OH 6yIh PreSen StUdy l7 cOmPOUn were ~shed, seven COmPOUn ofthem are new compoUnds.