The Preparation And Structural Characterization Of The TiO₂ Nanotube Array On The Orthopaedic Titanium Plate Surface

Objective: In order to explore a new way to prevention from and treatment on the infection of orthopaedic implants, the titanium plates’ surface was coated with Ti O2 nanotubes and its characterization as surface modification and carrier of antibiotics was investigated.Methods: Used the method of anodic oxidation which glycerin system as the electrolyte, titanium plate as anode, the orthopedic clinic platinum electrodes was used as cathode,. The space between the electrodes was 2 cm, temperature was adjusted about 20 ℃, ioniziation speed is 130 times/min. The polished under 40 voltage electronic pressure and passivatied titanium plate underwent 1, 3, 6, 12, 24, and 36 h anodic oxidation respectively. After drying, the nanotube arrays of titanium plate surface and morphology were observed under scanning electron microscopy(sem) Ti O2, and measured its diameter and length. Under the macro look observe its change over time, the surface of the array’s color will change. Using X-ray spectrometer analysis orthopaedic titanium plate surface of Ti O2 nanotube array elements. Will be the most stable form of nanotubes titanium plate in the muffle furnace heated to 300 ℃, by X-ray diffraction analysis(XRD) to see whether it has change its shape.Results: The method of anodic oxidation can be applied to manufacture Ti O2 nanotubes array on titanium plate surface in which glycerin system as the electrolyte. Different pipe diameter, length and different shapes of nanotubes was observed under scanning electron microscopy(sem) at each time- point. About 6 h the nanotube array could be formed on orthopaedic titanium plate surface; as time went by, the nanotubes array formed gradually completely, the nanotube array could be obtained around 70-100 nm in diameter, length within the 300 nm Ti O2 nanotubes sequence at 24 h; after continue anodic oxidation, Ti O2 nanotube arrays collapse, wall cracks, pipe mouth closed. Visible changes of orthopedic titanium plate surface under the macroscopy showed surface color change from the silvery white, light brown to lilac from mixed with dark brown, dark blue, light blue mix. X-ray spectrometer analysis 24 h orthopaedic titanium plate surface was mainly composed of Ti O2 nanotube array elements(Ti 75.88% 75.88%, 20.16%, F O elements).The muffle furnace heated to 300 ℃of Ti O2 nanotube arrays by X-ray diffraction analysis(XRD), found that the nanotubes array from amorphous state into anatase type, shape stability.In the oxidation voltage 40 v, oxidation time 24 h, can be obtained form the most complete.Conclusion: The method of anodic oxidation method can be used to manufacture Ti O2 nanotubes array on titanium plate surface, which is more convenient and effective. Ti O2 nanotube array has stable morphology, hollow shape internally, and closed bottom at each end, with a larger contact surface area and characterization of high-temperature resistance, can be applied as modification and decorative carrier on implant surface, which provides a new way for developing new anti-infection implant.