Study On Synthesis Of Acetophenone

Aromatic ketone compounds are not only important chemical raw materials, but also they are intermediates for the generation of the useful primary, special chemicals and high economic value fine chemicals, agrochemicals, pharmaceutical and perfumes industry. Acetophenone commonly can be used as raw materials and solvent for organic synthesis, catalyst for olefin polymerization.A new polymer-supported molybdenum-dmpz catalyst was synthesized by PS-DVB, 3,5-dimethylpyrazole, MoO3 as raw materials, and the resulting catalyst was used in selective oxidation of alkyl aromatics to benzylic ketones. The effect of reaction time, reaction temperature, solvent kind and the influencing were investigated.The structure was characterized by FT-IR, SEM and TG The SEM image of the catalyst shows blocky shapes. Weight of the catalyst loss at 400 ℃ was only about 20%.When use PS-DVB[MoO(O2)2(dmpz)2] as catalyst, the reactions take TBHP as oxidant to synthesize acetophenone from ethylbenzene. With a molar ratio of ETB:TBHP at 1:3,94% selectivity of acetophenone and 99%conversion of ethylbenzene were obtained at 80 ℃ for 36h. The catalyst PS-DVB [MoO(O2)2(dmpz)2] presented high activity for selective oxidation of alkyl aromatics to benzylic ketones with TBHP.When use NHPI/PS-DVB[MoO(O2)2(dmpz)2] as catalyst, the reactions take O2 as oxidant to synthesize acetophenone from ethylbenzene. With A1BN as initiator,98% selectivity of acetophenone and 65% conversion of ethylbenzene were obtained at 80 ℃ for 4h. The catalyst NHPI/PS-DVB[MoO(O2)2(dmpz)2] presented high activity for selective oxidation of alkyl aromatics to benzylic ketones with O2.In these experiments, the supported catalyst can be reused for at least 5 times at the same reaction conditions without great loss of activity.