Uniform Magnetic Field On The Process Of Dna Replication Of Device Design

With the pollution of electromagnetic fields on human existence environmental aggravating, scientific research are very interest in the possible biological effects of electromagnetic fields on the organisms. As the living environment where people are in the field of diversity, its effect on the biological organisms are very complex, which the effect on the cell cycle by electromagnetic fields is one of the important issues.When osteoblast were cultured and put in different forms of magnetic field,the researchers found that the cell cycle were changed, S-phase percentage were significantly higher as compared with control, but the specific mechanism of the effect on the cell cycle by magnetic field is not clear. The researchers speculate that the cell DNA synthesis is impact and regulated by the magnetic field, which leading to its synthesis becoming faster, thus the cells in S phase increased, but the speculate lack of firm evidence. The paper reported frequency magnetic field can give rise to epithelial cell DNA double-strand breaks, speculated that the magnetic field affect the biochemical and enlarge the process, indirectly damage DNA, but the specific mechanism is not yet clear.. In order to explore the effect on DNA synthesis and DNA double-strand breaks by magnetic field, We chose a relatively simple uniform magnetic field, study the affect on DNA synthesis and DNA double-strand breaks by such magnetic field, conclused that this impact related to magnetic field strength. In order to verify the conclusions, need to design a uniform magnetic field strength devices, and can control the temperature of the magnetic field area. this combination of knowledge, we related knowledge, and design the magnetic field devices.The main task of S-phase cells is DNA replication. In the process of DNA replication rotation, with the advance copy fork, front-end DNA molecule will produce torque, in order to release the accumulated torque, the double-stranded DNA molecules which is the front fork will appear special forms of exercise so as to release torque. and ensure the normal DNA replication. DNA is the biological macromolecules,negatively chargedthe on lateral, when the copy process been in a magnetic field, that will be the role of Lorentz force, which leading to changes in speed of DNA synthesis and thus the entire DNA molecule replication process will be interference, cell cycle will also change. On the basis of the phenomenon observed by the biological effects of magnetic team,and combination of the specific characteristics of DNA replication, This article theoretically discussed the affects on the uniform magnetic field on the DNA replication process,and found that uniform magnetic field will increase the speed of DNA synthesis, at the same time result in changes in the structure of DNA.At present, in order to in-depth study the mechanism of the affect on organisms by electromagnetic fields , the researchers often use relatively simple form of the magnetic field as outside interference magnetic fields, such as: static magnetic fields, alternating magnetic fields, pulse magnetic fields and high-frequency magnetic field. with the need, the researchers used are: permanent magnets,electromagnetic Helmholtz coils and solenoids as magnetic field devices. Permanent magnet can provide for a maximum intensity of the magnetic field around Tesla, Helmholtz coils and solenoids can provide alternating magnetic field or relatively uniform magnetic field, and solenoids can also be used to provide strength for the solenoid around 10 Tesla. Various magnetic field devices have a certain scope, this article from the perspective of physics, analyse the characteristics of the each device, with magnetic characteristics of each and magnetobiology research, we summed up a more practical magnetic field devices, According to the experiment requirements, design a practical magnetic field devices which can provide uniform magnetic fields, and take a solution which can control the temperature of the magnetic field of regional. Through computer simulation model,we find that the magnetic field in the device field is consistent with the expected results, through the actual model of temperature detection, confirmed the temperature control is practical. The uniform magnetic field devices is made up of power, solenoids, the water cycle, focusing on the solenoid and the water cycle temperature control device design.