Study On The Synthesis And Application Of New Silica Molecularly Imprinted Composite Material

Molecularly imprinted polymers (MIPs) is a highly cross-linked mesh material withthree characteristics of a predetermined resistance，specificity and practicability，which canbe able to match with a specific target molecule either in the spatial structure or bindingsites，and can identify the target molecule and its structure similar material．The materialcan be stable in acidic conditions，basic conditions and other harsh environments．Thematerial can also be stable in high temperature and high pressure，which is a material withexcellent mechanical properties．During the past two decades，The new type molecularlyimprinted composite materials were synthesized with the fully integrated of molecularimprinting technology and functional nano-materials，making the properties of eachmaterial fully integrated to work best．From the angle of the use of pesticides and environmental pollution，the paper selectsthe pesticides quinclorac and2,4-dichlorophenoxyacetic acid that are closely related tohuman life as the objects of the study，the paper also selects6-methylcoumarin which isspice additives as an object of the study．The paper prepared two kinds of highly selectivepesticides molecularly imprinted polymer，laid a certain foundation for the fast andefficient pesticide monitoring and analysis．The study is divided into the following several sections：1．Firstly，we introduced some basic concepts and the principles of molecularimprinted techniques．Secondly，the methods of preparation of molecular imprintedpolymers were reviewed．Specially，the preparation of surface molecularly imprintedpolymer were introduced in detail．2．Nano-molecularly imprinted polymers (MIPs) had been prepared by a one-stepswelling polymerization method in aqueous system using nano-polystyrene microsphereswhich was gained by a dispersion polymerization as seeds and using Quinclorac astemplate molecules． The results showed that the particle size of nano-polystyrenemicrospheres can be controlled between100~150nm and the particle size ofnano-molecularly imprinted polymers can be controlled at below300nm．3．We prepared mono-disperse SiO2particles，the average particle size of which isabout180nm．MPS-SiO2were prepared with a silane coupling agent MPS，and thenMPS-SiO2were applied to prepare PMAA-SiO2composite material with the sol-gel in-situpolymerization methods．Novel molecular imprinted composite material were prepared using PMAA-SiO2composite material as seeds and using6-methylcoumarin as templatemolecules．The results showed that Obtained surface molecular imprinting compositematerials can effectively adsorbed6-methylcoumarin molecules．4．Firstly Mono-disperse SiO2particles were prepared，the average particle size ofwhich is about200nm．Secondly APTS-SiO2were prepared with a silane coupling agentAPTS．Furthermore，APTS-SiO2reacted with acryloyl chloride，and AA-APTS-SiO2composite material were prepared．Another novel molecular imprinted composite materialwere prepared using AA-APTS-SiO2composite material as seeds and using2,4-dichlorophenoxy acetic acid as template molecules． The results showed that2,4-dichlorophenoxy acetic acid can be effectively adsorbed by obtained surface molecularimprinting composite materials．...