Research On Hybrid Structure Cluster System Based On Bioinformatics Application

Since the whole genome sequencing possible, the genomic structure Notes (including understanding of the genomic DNA of the gene composition, Structure and control components) as bioinformatics research important issues, As genome annotation system structure of the enormous amount of computation, needing high performance computing resources for genomic structure calculation of the Notes.Currently bioinformatics research institutions commonly used in the high-performance computing systems mainly the following two aspects : high cost structures, poor cost performance, the budget is limited laboratory is a heavy burden; while technical standards is not open, leading to software management difficulties, hardware scalability and high maintenance costs later.To solve the problems above, doing the following : erection of a suitable application of bioinformatics cluster-based revenue resources management middleware OSCAR cluster system. The current hardware technology, the basis of demand for hardware selection, Special unified view of the current structure of the cluster of insufficient PC / SMP server hybrid structure of the program. Clusters of related software selection and the experiment, focusing on the cluster resource management middleware, Selection process has done a lot of experiments to test the system compatibility. Selection of the hardware and software for system integration and system parallel computing environment for the test. In the process of integration, overcome a Linux software package dependence technical difficulties. Use of international standards on the LINPACK floating-point calculation of the cluster properties of the test, Results of the analysis and review to verify the cluster computing performance and scalability whether it meets the requirements. Developing a DNA-C / G content of PBS cgpbs procedure, helping bioinformatics scholars to deploy complex bioinformatics software for a certain exploration in the cluster system of parallel computing environment.