Research On Self-assembly Bisphenol A Molecularly Imprinted Electrochemical Sensor

Because of the mutagenic, carcinogenic, teratogenic and endocrine disrupting effects, bisphenol A (BPA) has been listed as a typical endocrine disruptor. Owing to the complexity of BPA environmental samples, highly sensitive and selective detection methods become the key issues restricted related studies.Based on the specific recognition ability of molecularly imprinted polymers (MIPs), a novel electrochemical sensor with high sensitivity and selectivity was constructed for detection of BPA. By the approach of self-assembly, molecular imprinted polymers (MIPs) have been synthesized with BPA as template molecule,3-aminopropyltriethoxysilane (APTES) as functional monomer and tetraethoxysilane (TEOS) as cross linker. The MIPs film was fabricated onto an Indium tin oxide (ITO) electrode (MIPs-ITO). The MIPs film was also fabricated onto a gold electrode which modified with single-wall carbon nanotube and ionic liquids (MIPs-Au).The BPA imprinted electrodes were characterized by AFM and FT-IR. The affinity and selectivity of the electrochemical sensors were characterized by cyclic voltammetry (CV). MIPs-ITO electrode was linear to the concentration of BPA in the range from 0.5 to 50μg L-1 and the detection limit was 0.094μg L-1. Furthermore, MIPs-ITO electrode showed low response to the interfering compounds. MIPs-Au electrode was linear to the concentration of BPA in the range from 0.5 to 70μg L-1 and the detection limit was 0.072μg L-1. At the same concentration, the current response of BPA at MIPs-Au electrode was 23.37,11.09,24.39 and 26.99 times that of phenol, p-aminophenol, p-nitrophenol and p-Tert-butylphenol respectively, which indicated that the MIPs-Au electrode performed excellent selectivity.By the approach of self-assembly, MIP film has been synthesized fabricated onto electrode which modified with single-wall carbon nanotube and ionic liquids. This study will provide important technical support to rapid and highly sensitive field analysis of BPA in water, and has important significance for environmental risk assessment and early warning of environmental emergencies.