Analysis Of Curative Effect Of Coronary Intervention On Maintenance Hemodialysis Complicated With Acute Coronary Syndrome

Purpose:To determine if percutaneous coronary intervention(PCI) is superior to drug therapy alone in patients with acute coronary syndrome(ACS) who underwent maintenance hemodialysis(MHD). Material and method:Between January 2008 and July 2014, total of 100 patients with ACS who underwent MHD were enrolled in General Hospital of Shenyang Military Region. Patients were randomly assigned to receive PCI or drug therapy alone in 1:1 ratio. In the PCI group, dual antiplatelet therapy(DAPT) comprising aspirin and clopidogrel was receivedafter PCI.In the drug therapy group, patients = use aspirin therapy alone. Other medication therapy of ACS was no difference. The primary end point was a composite of endpoint occurring within 1 year. The primary safety and efficacy points were the major bleeding(TIMI classification), stent thrombosis, any re-hospitalization for cardio-cerebrovascular disease,the value of left ventricular ejection fraction(LVEF). Results: 1.There was no significant difference between the two groups on PoCE(20%vs21%,P=0.680). 2.The results were statistically significant in the rehospitalization for cardio-cerebrovascular disease. The rate of re admission was significantly lower(50% vs 30%,P=0.040). 3.There was no statistically significant difference in total bleeding(6%vs4%,p=0.740)and thrombotic events between two groups(4%vs4%,p=1.000). 4.After 1 years into the group, there was statistically significant differences in LVEF values between the two groups.(52%vs49%,p=0.048) Conclusion: 1. PCI is safe and effective in patients with MHD and ACS. 2. PCI can significantly improve patients with MHD and ACS the symptoms, quality of life and prognosis, reduce the angina and hospitalization times with cardiovascular events. 3. DAPT is saft and does not increase the risk of bleeding in patients with MHD and ACS..