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Professor Zhao Chun 's Academic Thought And Clinical Experience And Clinical Study On Treatment Of Hyperlipidemia With Phlegm And Blood Stasis Syndrome

Posted on:2016-08-10Degree:MasterType:Thesis
Country:ChinaCandidate:Y B PuFull Text:PDF
GTID:2174330485492730Subject:Traditional Chinese Medicine
Abstract/Summary:PDF Full Text Request
1. Summary Zhao Chun professor’s academic thoughts origin Mentor Zhao Chun professor of clinical, graduated from kunming medical college in 1964, in 1980 graduated from the yunnan institute of traditional Chinese medicine western medicine leave learning institutes of traditional Chinese medicine(two-year).System to study the Chinese and western medical theory and clinical interdisciplinary knowledge, laid the solid Chinese and western medicine theory and professional knowledge base. For more than 50 years clinical tutors classic, with teacher, do, once in the yunnan province famous traditional Chinese medicine Xu Zijian, Li Xiaopu, Zhu Ge Lian Xiang, etc. Under the guidance of professor Dai Huifen, studied the huangdi neijing, "typhoid miscellaneous disease theory", "science of seasonal febrile diseases", "huang di" and so on many TCM classics, eclecticism, knowledge. Mentor in long-term clinical practice, persist in learning and mastering modern traditional Chinese medicine, combine traditional Chinese and western medicine medical exploration, new progress and new theory, new technology and new therapy, pay equal attention to Chinese and western medicine, the organic combination of the two, achieve mastery through a comprehensive study, development and innovation, and constantly improve the level of theory and professional ability, the tutor academic ideas influenced the formation, development and mature.2. Professor Zhao Chun academic thoughts and clinical experience and research 2.1 Academic thought 2.1.1 "Holistic concept" is the basic idea of teacher academic thought.Tutor thinks that the human body is a complex, multiple, self adjusting of the steady state system, to be affected by the natural environment and social environment, emphasize its disease is due to disorders a balance of Yin and Yang, disorder of five zang-organs system regulation, meridian balancing function disorder, such as the happening of the disease in its own control system disorder, attaches great importance to the coordination of Yin and Yang and viscera function, treatment is given priority to with adjusting therapy, by inside and outside the body upright against the pathogens and achieve the goal of restoring normal human body dynamic balance, which "is" Yin pingyang secret, spirit. 2.1.2 "Syndrome differentiation" is the mentor of important ideas and methods in diagnosis and treatment in traditional Chinese medicine, "cure" is the basic criterion in diagnosis and treatment of the instructor.Teacher points out that the syndrome differentiation and treatment is understanding the basic principle of the disease and treatment of diseases, traditional Chinese medicine is the embodiment of the combination of theory and practice, is in France medicine clinical application;Teacher pointed out that in the complex clinical manifestations, must want to explore the root causes of disease, so as to take in the right way to cure to determine root cause of disease.Master the regular pattern of specimen transformation, principal contradiction always catch disease, can cure this disease. 2.1.3 Tutor is good at using Chinese medicine "cure not ill" thought to guide medical practice.Teacher pointed out that "cure not ill" contains two meanings: one is prevention development emphasizes keep fit, prevent the happening of the disease;2 it is both disease prevent its spread after the change, emphasis on early diagnosis and early treatment, the evolution of disease control in a timely manner. 2.1.4" combined disease " is the core of methodology for teachers of Chinese and western medicine combined with diagnosis and therapy.Teacher pointed out that the combination of disease and syndrome differentiation is mainly refers to the syndrome differentiation of traditional Chinese medicine, western medicine disease, the method of combined disease.Paid attention to when teachers in clinical use of Chinese and western medicine the reduced clinical information collection, "dual diagnosis, the diagnosis is often first after illness syndrome differentiation, and combining the macroscopic syndrome and microcosmic syndrome differentiation, it is not only beneficial to expand ideas, provide optimal treatment for patients, and to grasp the condition changes, and outcome, prognosis is good. 2.1.5 Keep pace with The Times, follow the ancient and not old, inheritance develop innovation is a distinctive feature of academic thought of the instructor.Mentor stressed the dialectical thought should not only carry forward the traditional Chinese medicine, and to keep pace with The Times, innovation and breakthrough.From the experience of ancient medicine and should actively absorb the use of modern science, philosophy and so on the latest achievements of application of the advanced ideas and methods, make scientific thinking, ideas, methods, combined with traditional Chinese medicine, to create a new thought of modern traditional Chinese medicine, the new theory, new method.Mentor for years, pay special attention to combine traditional Chinese and western medicine treatment the critical optimum treatment plan and treatment of the key links, highlight the features and advantages of traditional Chinese medicine and put forward the "emergency phlegm, phlegm disease much more urgent", "new disease can also into complex", "stasis points priorities", "syndrome differentiation is blood stasis", "bacteria/poison/inflammation/dirty" and put new academic point of view, etc. 2.2 Clinical experience 2.2.1 Experience of prevention and control of sclerosis of arterial congee appearance(AS) Zhao Chun professor pointed out that, AS is a chronic, progressive, the mutation inflammation, acute disease, its pathogenesis is very complex.AS the AS the research progress and understanding of change, innovation, the coronary heart disease prevention and control of strategy, foreign scholars put forward "from vulnerable plaques to vulnerable patients" new concept of Zhao Chun professor think that the idea of change and advocates the overall concept, traditional Chinese medicine for the appropriate laws and focus on prevention of thought.Mentor is pointed out that deficiency, phlegm and blood stasis is AS the main etiology and pathogenesis, toxin factor play an important role in developing the AS material, put forward the "in" therapeutic principles and methods, advocated "pass" to clear phlegm soft firm, relieving material blood know luo for treatment;"Fill" with the spleen yiqi, tonic kidney for treatment.Emphasizes the play many link, the advantage of multiple target integral adjustment of Chinese medicine and combining the characteristics of targeted therapy of western medicine, should pay attention to keep long-term comprehensive treatment in patients with vulnerability.Zhao Chun professor Lin will often AS syndrome of phlegm obstruction pixu(spleen deficient), and qi stagnation and blood stasis, phlegm and blood stasis block, wet poison inside, liver and kidney Yin deficiency, spleen kidney Yang deficiency of differentiation, mentor stressed the card type often mutually and clip, consideration should be paid attention to when treating. Have the experience of the AS intervention from the risk factors of traditional pattern treatment to prevent or reverse plaque progression, treatment "artery" and "risk factor" is not only the change of management mode, namely + vascular risk factors intervention(intervention) management, especially the protection of vulnerable patients(blood, blood vessels, protect, cerebrovascular protection), for vulnerable patients have good protection of traditional Chinese medicine, this is to prevent and control AS a new concept. 2.2.2 The prevention and treatment of hypertension Mentor, points out that the disease belongs to Chinese medicine will be a headache or dizziness.Cause with modern imbalance, diet not festival, internal injuries is deficient and so on.Organs such as liver and kidney Yin and Yang imbalance, cardio-cerebral kidney damage as its key, pathological factors are wind, fire, phlegm, blood stasis, deficiency.Its disease is on the virtual to real, more factors.Liver and kidney deficiency as the imaginary, liver Yang syndrone, wind, wind phlegm are the one for real fire. Because the etiology and pathogenesis, pathology of hypertension is very complicated, only for patients with simple treatment is difficult to achieve the ideal effect, only combine traditional Chinese and western medicine comprehensive treatment measures(including sexual lifestyle intervention treatment, drug therapy, etc.) for patients with overall adjustment to improve the disease control rates, a satisfactory curative effect.High blood pressure level 1, low-risk patients with moderate should seriously change way of life, and according to the TCM syndrome differentiation and treatment, most patients can achieve treatment goals;Hypertension 2, level 3, high risk and very high-risk patients must begin immediately to high blood pressure and the coexistence of risk factors and clinical situation of drug therapy, in order to achieve treatment goals.To give full play to the advantages of Chinese and western medicine respectively, achieve complementary advantages, to develop and improve the diagnosis and treatment of traditional Chinese and western medicine combined with optimization scheme, the implementation of individualized treatment and persistence.Mentor for syndrome differentiation of the disease is divided into the essence of liver Yang, phlegm turbidity resistance, liver and kidney deficiency, blood deficiency, phlegm and blood stasis resistance winding five card type, each card type can be alone, can also and see each other, must search out the disease, syndrome differentiation treatment. My experience to the Chinese medicine has unique advantages in prevention and treatment of hypertension, reflects the system much more links overall adjustment, the characteristics of syndrome differentiation in addition to the flexible use of traditional Chinese medicine decoction can choose when to justify the modern Chinese native medicine preparation, in order to strengthening prevention and control of hypertension and target organ damage, improve symptoms, improve quality of life. 2.2.3 The experience of treating multiple organ dysfunction syndrome Multiple organ dysfunction syndrome(MODS) refers to acute severe infection and the infection factors induce systemic inflammatory response syndrome(SIRS), leading to the body at the same time or ensued after 24 hours of two or more organ function reversible damage clinical syndrome.Mentor, points out that MODS can know the traditional Chinese medicine "dirty" dragon’s disease category, dirty and whose disease refers to many viscera and/or syndrome, show a variety of severe syndrome, multiple viscera essence failure(syndrome, lung failure, block and repulsion, fact, heart failure, god faint, etc.). The formation of the disease, mostly due to the blank deficiency of vital qi, viscera function disorder, qi and blood, Yin and Yang imbalance, complex due to exogenous evil poison, severe trauma, major surgery such as heat, poison, blood stasis and wet on the body, evil is virtual to real, are too numerous to evil, and down inverse chaos, two or more than two dirty really seriously damaged organs, should the disease desire from the desire of Yin and Yang.Can be summarized as is poison damage, collaterals stasis, qi activity inverse chaos, viscera function failure.Medicine, it is considered that the main mechanism of MODS occurred is endotoxin induced systemic inflammatory response syndrome(SIRS), SIRS/CARS compensatory anti-inflammatory response syndrome)(imbalances, immunosuppression, vascular endothelial injury, microcirculation, blood coagulation and fibrinolytic system imbalance, tissues and organs damaged especially intestinal barrier function is impaired, pathophysiological link is sepsis occurrence, development, increase in the key of MODS. Mentor emphasize TCM pathogenesis of MODS always belong to "evil is virtual to real," is the total therapeutic principle "stabilizer" and "evil spirits", syndrome differentiation and treatment is divided into positive and deficiency syndrome.Empirical including toxic heat flourishing(such as phlegm heat indicates pulmonary syndrome, liver and gallbladder damp and hot, Yang Ming relieving empirical), heat the camp fact, two burnt syndrome, qi and blood stasis, etc.;Deficiency syndrome include both heart and lung spleen and kidney deficiency syndrome, qi and Yin syndrome, sun be the spirit and anxiety by consumed, Yin jue Yang to take off the card, etc.Is the most prominent MODS have different organs damaged critically ill change the performance such as: take off the card(shock), lung failure, acute lung injury/acute respiratory distress syndrome(ALI/ARDS), block and repulsion(acute renal dysfunction), bi(acute gastrointestinal dysfunction), the fact() blood coagulation dysfunction, heart failure, acute heart failure, god faint(such as acute liver, brain dysfunction), mentor stressed shall timely for each viscera function damage or failure disease treatment based on syndrome differentiation.Because of MODS in a critical condition, combine traditional Chinese and western medicine comprehensive prevention measures should be taken, thus improve the MODS rescue success rate, reduce the case fatality rate. The author realized that traditional Chinese medicine treatment of MODS, unique advantage, should pay attention to correct application in MODS rescue process.Use of traditional Chinese medicine concept of "whole", "dialectical treatment", "cure not ill" ideological understanding MODS, rich can make a diagnosis and give treatment strategy, ideas and methods.MODS basic of traditional Chinese medicine syndrome differentiation system is the six-channel differentiation, wei qi camp blood syndrome differentiation is given priority to, with a philosophical tradition, defend the change regularity of gas blood camp and the rule of the zang-fu syndrome differentiation. "Put forward by the tutor bacteria/poison/inflammation/dirty and cure" new theory, new treatment is with antibiotics antibacterial sterilization, with qingrejiedu, blood know luo, relieving heat treatment and removal, and the formulas, the degradation of toxins, adjust the inflammatory mediators, repair endothelial damage, restore blood coagulation and fibrinolysis system of dynamic balance;To chang qi, replenishing qi to save Yin, hui Yang solid off treatment and restore the body’s immune function, the formulas to protect vital organs.This new therapy should be as the prevention and treatment of severe sepsis and septic shock, the important way of MODS and throughout the whole course of the application. 2.2.4 Professor Zhao Chun experience research Records of ancient character now, more than her own experience, unique formula, used for the corresponding disease, curative effect is distinct, the studies on these prescriptions, makes the author more deeply understand the academic thought and experience of the tutor and drug laws. Jing Hu unclogged arteries party Composition: rhodiola, giant knotweed, notoginseng, leeches, tuckahoe, whitehead. Efficacy: promoting blood circulation to remove blood stasis, qi tong, detoxification and clear phlegm. Indications: for the prevention and treatment of hyperlipidemia, hypertension, coronary heart disease, obesity, and the block phlegm and blood stasis syndrome of sclerosis of arterial congee appearance, etc. Ordering party being dizzy flat Composition: gastrodia elata, uncaria, radix puerariae, radix scutellariae, poria cocos, chrysanthemum, haliotis, eucommia bark, mulberry parasitism, atractylodes, pinellia, radix cyathulae, lotus, salvia miltiorrhiza, liquorice. Efficacy: smooth liver latent Yang, nourishing liver and kidney, invigorate the circulation of phlegm. Indications: for the treatment of liver Yang syndrone, disease see: headache head bilges, tinnitus and insomnia much dream less;Or hemiplegia, eye askew mouth, red tongue, pulse string.Now used in the treatment of hypertension, cerebral apoplexy, speech Mr Disease such as dizziness, headaches. The dragon centering party Composition: keel, raw oysters, purple quartz and spikenard, pseudostellaria root, dwarf lilyturf, salvia miltiorrhiza, zizyphus jujube kernel, platycladi seed, broiled polygala, main licorice. Efficacy: qi and nourishing Yin and calming nerves nerves, nervous after pulse. Indications: for the treatment of qi and Yin injury syndrome, have heart palpitations, insomnia, much dream, chest condition, dysphoria, spontaneous perspiration and other performers.3. Professor Zhao Chun Jing Hu unclogged arteries of the treatment of hyperlipidemia phlegm stasis mutual junction clinical studies Objective: to study the Jing Hu unclogged arteries party treat hyperlipidemia phlegm and blood stasis and the clinical curative effect and security of the "certificate. Methods: 60 patients with hyperlipidemia phlegm stasis mutual junction Jing Hu flux pulse party group 30 cases were randomly divided into test group and control group: the capsule group 30 cases, blood lipids, TCM syndrome before and after treatment was observed.After the observation, the summary and analysis of data, using SPSS16.0 statistical software for analysis. Results: Group lipid control effectiveness is 86.67%, and the control effectiveness is 83.33%, show Jing Hu unclogged arteries can reduce serum TC TG, LDL- C, and atherosclerosis index(AI), can also increase HDL- C at the same time, two sets of adjusting blood fat effect, results are similar between the two groups has no statistical significance(P > 0.05).By comparing two groups of patients after treatment of TCM syndrome integral are significantly reduced, through the software analysis statistical comparison and statistical comparison between groups within the group had significant difference(P < 0.05), the results also show the TCM syndrome integral differential treatment group than the control group.Experimental Chinese medicine clinical symptoms improved effectiveness is 90.00%, the control group was 80.00%, the experimental results show that the two groups can improve the patients clinical symptoms of TCM, and professor Zhao Chun Jing Hu unclogged arteries party has obvious improvement condition of syndromes, the curative effect was significantly higher: capsule group, and the result differences with significant statistical significance(P < 0.05).Group lipid control effectiveness is 86.67%, and the control effectiveness is 83.33%, show Jing Hu unclogged arteries can reduce serum TC TG, LDL- C, and atherosclerosis index(AI), can also increase HDL- C at the same time, two sets of adjusting blood fat effect, results are similar between the two groups has no statistical significance(P > 0.05).By comparing two groups of patients after treatment of TCM syndrome integral are significantly reduced, through the software analysis statistical comparison and statistical comparison between groups within the group had significant difference(P < 0.05), the results also show the TCM syndrome integral differential treatment group than the control group.Experimental Chinese medicine clinical symptoms improved effectiveness is 90.00%, the control group was 80.00%, the experimental results show that the two groups can improve the patients clinical symptoms of TCM, and professor Zhao Chun Jing Hu unclogged arteries party has obvious improvement condition of syndromes, the curative effect was significantly higher: capsule group, and the result differences with significant statistical significance(P < 0.05). Conclusion:Through clinical observation Jing Hu unclogged arteries to the spleen phlegm, invigorate the circulation of blood know luo for method can effectively regulating blood lipids in patients with dyslipidemia, reduce the AI, the experience side to treat hyperlipidemia phlegm stasis mutual junction is safe and effective, is worth further research.
Keywords/Search Tags:academic ideas, Clinical experience, Zhao Chun, Hyperlipidemia, Jing Hu unclogged arteries part
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