Clinical Study On Treatment Of Idiopathic Pulmonary Fibrosis With Yangyin Yifei Tongluo Pills

Objective:To observe the clinical efficacy of the yangyin yifei Tongluo Wan treating pulmonary interstitial fibrosis.Method:72 patients were randomly divided into the treatment group with yangyin yifei Tongluo wan and the control group with N-acetylcysteine. The procedure was three months, And Comparing respect, the main symptoms,signs, pulmonary function. HRCT scores and the 6-min walk test. Of patients in the two groups. And finally it was concluded that the overall effect of the yangyin yifei Tongluo wan to treat pulmonary interstitial fibrosis.Results:1.Disease efficacy:pulmonary fibrosis patients after treatment with yangyin yifei Tongluo wan for 3 months,34 cases,3 cases improved,21 cases stabilited,10 cases are invalid, The total effective rate was 70.59%.The yangyin yifei Tongluo wan in improving IPF patients with clinical symptoms, the remission of the disease and to maintain stable disease has a certain role;2.Syndrome of traditional Chinese Medicine efficacy:patients after 3 months of yangyin yifei Tongluo wan treated,0 cease were cured,5 cease were main effectived,20 cease were effectired, ineffective in 9 cease, The total effective rate was 73.53%, The patients with qi and yin deficiency phlegm obstruction and blood stasis syndrome improved;3.Pulmonary fuction effect:After 3 months of treatment. The Total lung Capacity and vital Capacity Forced and diffusion Capacity for carbon monoxide of the lung all showed no statistical difference.4.6-min walk test effect:After 3 months with treatment, The treatment group with yangyin yifei Tongluo wan in the score were significantly improved. It clined yangyin yifei Tongluo wan has a gignificant effect increasing activity to lerance.5.HRCT effect:The HRCT results showed there was no significant difference berween groups (P> 0.05).6. The effect of dyspnea:According to the breathing difficult curative effect evaluation criteria, after 3 months after the treatment of interstitial pulmonary fibrosis respiratory difficulty degree, treatment of 34 patients, including 6 cases, effective in 16 cases,12 cases are invalid, efficiency of 64.7%, Chinese traditional medicine of yangyin yifei TongLuo Wan on dyspnea has a certain improving effect.Conclusion:Denpending yangyin yifei Tongluo wan to treat pulmonary interstitial fibrosis exactly achieved clinical efficacy in a certain degree. It can improve the clinical symptoms and signs significantly. Maintain the stable condition of the disease, especially patients’ activity tolerance can be improved greatly.Significance:Pulmonary fibrosis is to diffuse alveolar units of chronic inflammation and fibrosis is the main pathological features are a class of diseases.According to its pathogeny, interstitial pulmonary fibrosis Can be divided into two Categories:the definite one Can belong to the primary disease or be Called to secondary pulmonary interstitial fibrosis; the other one which has umknown pathogeny is defined as idiopathic pulmonary fibrosis. This disease is difficult to Conquer. There ane no ideal drugs in the treatment of IPF. Glucocorticoid is the mainly treatment in western medicine, with inevitable side effects. There are many Traditional Chinese Medicine(TCM) theories and methods of treatment of this disease. the yangyin yifei Tongluo Wan Can treatment in patients with IPF. It has a significant effect.