Discrimination on disease and damp-syndrome is the topic which is researched and discussed all the times in the traditional Chinese medicine field. Fingerprint chromatograms of fresh urine derived from healthy people, patients with damp-syndrome and patients with non-dampsyndrome are researched in this paper. And a series of studies are performed on these fingerprint chromatograms and certain achievements have been gamed.First, theory and characteristics of chromatography are explored in the paper. The method based on math model, which is established according to fingerprint chromatogram, is used to analyze the actual significance of common peak, overlap rate and n-strong peaks.Secondly, some methods on cluster analysis have been studied and analyzed. And the methods can be divided into portioning method, hierarchical method, density-based method, grid-based method and model-based method.Portioning method: Construct a partition of a database D of n objects into a set of k clusters and each portioning means a cluster with the time complexity of O (n2), where k |