The Clinical Study On The Parenteral Nutrition Support Of Severe Premature Infant

Objective:To investigate the curative effect of parenteral nutrition of severe premature infant.To investigate the curative effect and safety of parenteral nutrition of early and effect of suck with comfort nipple to intolerance of feeding and parenteral nutrition. Methods:To choose the high risk of premature infant compare Inability tolerance enteral nutrition or enteral athreptic with body weight larger than 1 kg and larger than 2.5 kg, conceptus age larger than 28 week and larger than 37 week. In 60 cases. The random divides into 2 group, Experimental group add to amine acid and fat emulsion after birth in 24 hours. Observation group adopt to orthodox parenteral nutrition, amine acid and fat emulsion are applied after birth in 72 hours. according to pathogenetic condition, micro-feeding and non-trophicity imbibition are gave as early as possible. premature infant with disease are examed blood routine, liver functions, bilirubin, triglyceride, total cholesterol, urea nitrogen, electrolytes after birth in 1day and 7day. body weight, micro-glucose in blood are monitored, calorie is account, Enteral Nutritional calorie time achieving 292.6KJ/(kg.d) become enteral nutrition time, parenteral nutrition time, hospital day. Feeding tolerance and excretion of meconium, parenteral nutrition correlated complication and after recovery are observed. Results:(1) premature infant are cured with shorten in 60 cases are recovered the birth body weight in (6.60±1.26) day, body weight is increased with parenteral nutrition Conclusion in 58cases. The average incrase (21.5±5.14) g/d every day.58 cases are cured, recovery rate is 97.5%(58/60), fatality rate is 3.3% (2/60), PNAC incidence rate is 3.3%; (2) premature infant with disease in rimental group recover birth body weight time, total enteral nutrition time, parenteral nutrition time, hospital day is shorter than observation group (P<0.01), calorie in 3 and7 day is higher than observation group (P<0.01), metabolism complication and aspirated pneumonia cases of premature infant is shorter than observation group (P<0.05), Body weight descended amplitude is non-difference (P>0.05); total bilirubin, direct bilirubin, total cholesterol, triglyceride, urea nitrogen with alike day after day in two group are not significant difference, (3) nose feeding with comfort nipple can decrease obviously gastric retention and advance meconium exhaustion and shorten parenteral nutrition time and advance transitionfrom parenteral nutrition to intestinal tract nutrition. Conclusion: parenteral nutrition can advance the growth development of severe premature infant and accelerate to increase in body weight and elevate recovery rate; the parenteral nutrition support of early, energetic, reasonable is beneficial and safety; nasogastric tube with comfort nipple imbibition is a eligible Feeding method of assistance.