Cox Analysis Of Clinical Prognostic Factors In 100 Patients With Breast Cancer

Objective: to investigate the value of clinical prognostic factors in 100 patients with breast cancer. Methods: The analysis was performed in 100 cases of the breast cancer treated from March , 2003 to March ,2005.The correlation of age, tumor size, axillary lymph node involvement, estrogen receptor status, progesterone receptor status, menopause status with prognosis of breast cancer was evaluated. Result: Kaplan-Meier Log-rank analysis revealed that 3/5-year overall survival rate and Disease free survival period of this group was significantly associated with age, menopause status ,axillary lymph node involvement, estrogen receptor status. Then cox analysis revealed that 3/5-year overall survival rate of these patients was significantly associated with age, menopause status , axillary lymph node involvement and tumor size,Progesterone receptor status, Human Epidermal growth factor Recepter-2 had no significant independent prognostic value. Conclusion: Our data demonstrated that age ,estrogen receptor status. axillary lymph node involvement were significant indicators of prognosis in breast cancer respectively and it was not demonstrated that tumor size, progesterone receptor status, human epidermal growth factor recepter-2 were significant prognostic factors.