Clinical Analysis Between TCM Syndrome And Related Indicators As Well As Glucose Control

Objective:(1)Summarize TCM syndrome in dialysis patients;(2)Compare related indicators differences in different TCM syndrome patients; (3)Analyze clinical significance of glucose control.Methods:Using cross-sectional study,we summarized TCM syndrome in118 dialysis patients. The difference of vascular endothelial function (FMD), load capacity (water load, OH), Subjective nutritional assessment (SGA), C-protein and other related indicators were compared in different TCM syndromes. According to HbAlc<7% standard,we analyzed the differences in residual urine volume, ultrafiltration, dialysis adequacy (KT/V total), FMD, OH, CRP, SGA malnutrition, and the incidence of peritonitis. At the same time,correlation analysis was made between fasting blood glucose and FMD, OH, CRP and other indicators.Results:1.In TCM deficiency syndrome, the spleen-kidney Yang deficiency syndrome, deficiency of both yin and yang, Qi and Yin deficiency syndrome have a more distribution, and blood stasis, damp, damp-heat syndrome have a more distribution of in TCM strong syndrome.2. Liver kidney yin deficiency syndrome has the highest incidence of malnutrition (60%). FMD in strong syndrome:None strong syndrome> damp turbid> heat-toxin syndrome> damp-heat> blood stasis (P<0.01). CRP:Damp> heat-toxin syndrome> damp turbid>blood stasis> no strong syndrome (P<0.05).3. Patients with good glucose control have a more residual urine volume greater (P<0.01), a lower ultrafiltration (P=0.013). KT/V was no significant difference(P=0.593).4.OH has a significant difference (3.3±2.2vs4.4±2.3, P=0.021) as well as CRP(5.3±4.4vs16.2±12.6, P<0.01) and FMD has no significant difference (7.4±3.6vs6.2±3.3, P= 0.087) in different glucose control patients.5. There is no significant difference in SGA prevalence of malnutrition (37.2%,3.8% vs30%,12.5%, P=0.190) and peritonitis rate (9.0%vs11.9%, P=0.291). in different glucose control patients.6.FBG showed a significant negative correlation (r=-0.283, P<0.01) with FMD and a significant positive correlation (r=0.267, P<0.01) with CRP. Conclusion:(1)The spleen-kidney Yang deficiency and blood stasis syndrome have a largest distribution; Liver Kidney Yin Deficiency patients have a higher proportion in malnutrition; Endothelial dysfunction is more serious in patients with blood stasis; CRP in damp-heat patients is higher than other syndromes, which may reflect a higher inflammatory state. (2)Good glucose control may slow further decline in residual renal function, reduce inflammation and to some extent,to improve the capacity and endothelial dysfunction.