Comparision Of Target Treatment For Type 2 Diabetic Mellitus With Different Therapy

Objective: To compare target treatment for type 2 diabetic mellitus with differrent insulin therapy. To compare target treatment for type 2 diabetic mellitus on a low-carbohydrate diet. Methods: The study is a randomised controlled tial. In insulin therapy, 103-cases of type 2 diabetic mellitus received an insulin treatment. The therapy of treatment: A group(32-cases)were treated with multiple subcutaneous injections of mixed insulin human analog lilyMix25, B group(47-cases)were treated with multiple subcutaneous injections of NovoMix30, C group(24-cases)were treated with Glargine quaque die. In diet therapy, sixty cases of type 2 diabetic mellitus were divided into two groups randomly, reseach group: 30 patients with type 2 diabetes were advised routine eatment of low-carbohydrate diet, control group: 30 patients with type 2 diabetes were advised on the treatment of the routine diabetic diet high-carbohydrate diet. Results: After 2 weeks, in insulin therapy, the blood glucose of three groups all dropped obviously (p<0.01); there were not obviously differences among three groups in glyeaemia control(χ~2=3.149, P>0.05); there were obviously differences among three groups in daily insulin costs(F=46.904,P<0.05); there were obviously differences among three groups in insulin dosi(sF=3.992, P<0.05); there were obviously differences among three groups in the risk of hypoglycemia(χ~2=6.766, P<0.05).After 2 weeks,in diet therapy, the levels of FPG,PPG of two groups all dropped obviously and the value of P were less than 0.01, but after treatment the levels of FPG in reseach group were lower than control group(P<0.05),the levels of PPG in reseach group decreased more obviously than control group(P<0.01), the incident of hypoglycemia in reseach group were lower than control group(χ~2=5.96, P<0.05);the glyeaemia control in reseach group were better than control group(Z=-3.645, P<0.01). Conclusion: In insulin therapy, the glyeaemia control were similar, Glargine has highest daily costs, lowest risk of hypoglycemia and least dose than the other group. In diet therapy, low-carbohydrate diet was found to be safe and effective to improve glyeaemia control of type 2 diabetes.