A Study Of The Relationship Between The Proportion Of Excision, The Gland Fossa After TURP And The Effect Of Treatment

Objective: 1,Study the relationship of urinary flow rate among different model of the prostate gland fossa. 2,Study the relationship of effect between the different proportion of excision,the different gland fossa of excision after TURP and the effect of treatment.Materials and Methods: 1,Model experiment: According to different volume, producing four kinds, tow groups of the glass model of crypt shape; according to different cross-sectional area, making five kinds, tow groups of geometric shape-model made by resin; according to same circle but different cross-sectional area, making eight kinds, tow groups of geometric shape-model made by resin. Comparing the relationship of urinary flow rate between different shape of model in every group. 2,Clinical observation: Follow up 125 patients after TURP. According to different proportion of excision of the gland tissue, dividing the patients into three groups, they are <40% group, 40% -60% group, > 60% group. After TURP, according to different shape of prostate, dividing the patients into three groups, they are cylindrical group, non-cylinder-like group. Comparing IPSS score, QOL score, Qmax between preoperative and postoperative among groups, and the endpoint of postoperative complications.Results: 1,Model experiment: In Glass model, Qmax total F = 1.17, P = 0.47; among the different form groups F = 0.59, P = 0.66; Qave total F = 4.82, P = 0.11, among the different form groups F = 0.73, P = 0.46. In Geometric model, Qmax total F = 12.2, P = 0.02; among the different form groups F = 0.64, P = 0.66; between group Bing and group Ding, F = 58.2, P = 0.02. Qave total F = 19.8, P = 0.01; among the different form groups F = 0.36, P = 0.83; between group Bing and group Ding, F = 97.8, P = 0.01. In Irregular model, Qmax total F = 204.5, P = 0.02; among the different form groups F = 53.2, P = 0.00; between group Wu and group Ji, F = 1263.5, P = 0.00. Qave total F=79.4,P=0.00; among the different form groups F=28.2,P=0.00; between group Wu and group Ji, F=437.5,P=0.00. Comparing the data of Qmax and Qave between 6 models J～O of group Wu and Ji, P<0. 05. Comparing the data of Qmax and Qave between group Wu and Ji with 6 models J～O , P﹥0. 05. Comparing the data of Qmax and Qave between P and Q of group Wu and group Ji, P﹥0. 05. 2,Clinical observation: The proportion of excision of preoperative(three group), compare the age, prostate volume, IPSS score, QOL score, Qmax, P﹥0. 05. The group of gland fossa of excision preoperative(two group), compare the age, prostate volume, IPSS score, QOL score, Qmax, P﹥0. 05. The data of the three groups that different proportion of excision, using analysis of variance of the randomized block design and tow-tow comparing, result: Comparing IPSS score, QOL score, Qmax between preoperative and postoperative each group, P<0. 05; Comparing group <40% and group 40%-60%, group >60% in postoperative, IPSS score, QOL score, Qmax, P<0. 05; Comparing group <40% and group >60% in postoperative, IPSS score, QOL score, Qmax, P<0. 05; Comparing group 40%-60% and group >60% in postoperative, IPSS score, QOL score, Qmax, P<0. 05. Comparing the effect between preoperative and postoperative, that different gland fossa of excision (tow groups):In tow groups IPSS score, QOL score, Qmax , compare between preoperative and postoperative, P<0. 05; Comparing IPSS score, QOL score, Qmax between group cylinder-shaped and group non-cylindrical shape postoperative P<0. 05. Comparing complications among the three groups that different proportion of excision: X2 =1.652, V=2, P=0.438. Comparing complications in the tow groups that different gland fossa of excision: X2 =13.144, V=1, P=0.000.Conclusions: 1,Model experiment: In glass model experiments, constant pressure, there are no close relationship between the measured flow rate value and the group of shapes, volume, but there are no close relationship between the measured flow rate value and the size of export path of the models, the min-path of whole pipe. In geometric resin model experiment, in the constant pressure and the same cross-sectional area, there are no close relationship between the measured flow rate value and the geometry of the model. But when the cross-section area of the model group is large, urinary flow rate values also are large. In irregular resin model groups, in the constant pressure and the same outer circumference, it is large of flow rate values in the cylindrical or nearly cylindrical. 2,Clinical observation:It has the some effects between cut prostate tissue ratio of 40% -60%, and > 60% after TURP. The effect of cut prostate tissue ratio of 40% -60% after is better than that of <40%. When cut out cylindrical crypt or similar cylindrical channel after TURP, the effect is reliable. For TURP, when the key part is cut in place, the surgery is safe and effective, and the complication is less, postoperative quality of life of patients is better, and the effect is reliable.