Clinical Investigation On 331 Cases Of Premature Rupture Of Membrane

Purpose:This study was undertaken to show the possible inducement and the effects of premature rupture of membrane(PROM)on neonatal and maternal outcomes.Methods:We selected 331 cases patients of PROM from our hospital from March 2009 to January 2010, retrospectively analysis. And 282 cases intact membrane delivery patients were selected as the a comparative analysis at the same times.①The experimental group was defined as PROM group.The matched group (group C) was defined as the intact membrane group.②The 331 cases PROM was divided into group A (≥28weeks, <37weeks) and group B(≥37weeks)with gestational weeks.③The group A and group B was separately divided into<24hours group and≥24hours group with the time of membranes rupture.Results:Infection could be one of the causes of PROM. The incidence rate of infection of group A was significant deviation this of group B(p<0. 05).The cesarean rate of group B was much higher than that of group A and group C(p<0.05).The rate of hyaline membrane disease of newborn, asphyxia neonatorum and perineonate death between group A and group B was significant difference (p<0.05). The rate of hyper bilirubinemia and infection of newborn of group B was much higher than group C (p<0.05). The incidence rate of chorioamnionitis was higher than when the membranes ruptured over 24 hours was much higher than when it was less than 24 hours of group B. The incidence rate of infection and chorioamnionitis when the membranes ruptured over 24 hours was much higher than when it was less than 24 hours of group B (p<0.05).Conclusion:1.Infection could be one of the causes of premature rupture of membranes.2. Premature rupture of membranes may be one of causes of cesarean rate rise up.3.The incidence rate of chorioamnionitis would increase when the membranes rupture over 24 hours in the PPROM.