Correlation Between Oxytocin Receptor And Pain In Patients With Endometriosis

Obiective:To investigate the expression of oxytocin receptors (OTR) in the ectopic and eutopic endometrium of women with endometriosis and its relationship with dysmenorrhea. Methods:To detect the expression of oxytoc in receptor in the normal and ectopy membrane of endometriosis and the health endomerum by immunohistochemistry. Results:Oxytocin receptor was expressed in endometrium from women with and without endometriosis.The expression of oxytocin receptor in patients with endometriosis with pain had higher expression than those of endometriosis without pain.The expression of oxytocin receptor in the group whose pain was severe was significantly higher than the group whose painw as slight. Conclusion:The overexpression of OTR in women with endometriosis may be one of the pathogenesis of dysmenorrhea, and it may be a new therapy target of dysmenorrhea in endometriosis in the further.