The Study Of Relation Of Carotid Artery Thickness And Levels Of Plasma Homocysteine In Hypertensives

objective:To understand the association of levels of plasma homocysteine in hypertensives with carotid artery thickness,gender,age,smoking,drinking,glucose and blood lipid.Methods:Select hypertensives 250 cases in March 2007-March 2008 in the People Hospital of Xin Jiang Autonomous Region, investigate of levels of plasma homocysteine, intima-media thickness(IMT), blood lipids, blood glucose, and smoking, drinking related risk factors, the subjects are divided into non-high HCY Group (≤15umol/L) and high HCY group(> 15umol/L).Results:①the levels of plasma homocysteine increased with hypertension in hypertensives②compare with high HCY group and non-high HCY group, the IMT of right internal carotid artery,left common carotid artery,left internal carotid artery are higher in high HCY group than non-high group, P<0.05; after divided by gender analysis, the IMT of right common carotid artery,right internal carotid artery,left common carotid artery,left internal carotid artery are higher in high HCY group than non-high group in male group, the IMT of left common carotid artery,left internal carotid artery are higher in high HCY group than non-high group in female group, P<0.05.③the levels of plasma homocysteine related positively with right internal carotid artery,left common carotid artery,left internal carotid artery, P<0.05, the levels of plasma homocysteine related negatively with HDL, P<0.05.Conclusion:The levels of plasma homocysteine are related positively with carotid artery thickness,negatively with high density lipoprotein and increased with hypertension in hypertensives.