The Clinical Value Of Fetal Tei Index In Preeclampsia

PURPOSE: Color Doppler echocardiography was used to measure fetal ventricu- lar Tei index of normal fetuses in the middle and late gestation and Tei index of varying degrees of preeclampsia fetuses to observe the trend and explore the clinical value of fetal ventricular Tei index in preeclampsia.MATERIALS AND METHODS: 193 sdudies from 20 to 41+6 gestational age were included in this research who visited doctors and were treated in the first hospital of soochow university from Feb 2009 to Dec 2009. There were 125 normal fetuses and 68 preeclampsia fetuses who were divided according to severity.There are 32 cases in severe preeclampsia group,14 cases in mild preeclampsia group,22 cases in gestational hypertension group. All fetuses were carefully examined with SIEMENS Antares Doppler ultrasound of left and right ventricular isovolumic time and ejection time, and conventional indicators of fetal.RESULTS: 1.There were no significant difference on average heart rate ,LV and RV isovolumic time, ejection time, Tei index in different gestational age groups of normal fetuse(sP>0.05); 2. Overall analysis of LV and RV Tei index showed a normal distribution, RV Tei index was slightly higher than LV Tei index, but no significant difference (P>0.05), while LV ejection time and isovolumic time were significantly smaller than RV ejection time and isovolumic time in normal fetuses (P<0.05);3. LV and RV Tei index of normal fetuses were not related to gestational age, average heart rate and fetal birth weight; 4. Left and right ventricular function were no significant difference between GH and normal fetuses (P>0.05); LV and RV isovolumic time and Tei index in MPE fetuses were significantly higher than in normal fetuses (P<0.05); Left and right ventricular function were significant difference between SPE fetuses and normal ones(P<0.05), and RV Tei index was statistically significantly higher than LV Tei index in SPE group(P<0.01);5. RV Tei index of SPE fetuses had the negative correlation with gestational age at birth, fetal birth weight, 1,and 5,Apgar score.CONCLUTIONS: Tei index can be used in the assessment of fetal ventricular function as a good indicator, especially in the assessment of right ventricular function;fetal global ventricular function is constant in the whole middle and late gestation; fetal left and right ventricular function in preeclampsia are impaired, especially in SPE; and right ventricular function was influenced heavier than left;Tei index has some clinical value in monitoring fetal distress,and forecasting the outcome of SPE fetus.