Study On MSCT Pulmonary Groud-glass Opacity And Sign In The Differential Diagnosis Of Benign And Malignant

Objective:Analysis of lung with focal groud-glass opcity(fGGO)of MSCT signs,designed to identify and further sun of malignant and benign fGGO the CT show similarities and differences,look for the more specific signs,to further improve the accuracy of clinical diagnosis fGGO.Method:80 cases with pathologically or cliniacal imaging data proved were reviewed.49 cases were maligant including 29 broncholoalveolar cell carcinoma(BAC)and 20 adenocarcinoma(of which 2 BAC cases with high or media differentiation).31 cases(341esions)were benign including 6 pulmonary contusion(71esions),17pneumonia(181esions),3atypical adeno-matous hyperplasia(AAH 4 lesions),3 organizing pneumonia,1 tuberculosis and 1 inflammatory pseudotumor。All cases were scaned by 16 or 64 multi-slice spiral CT with 0.625-5mm collimation. To analyze the size and distribution of lesion and the MSCT findings(shape,margin,interface, internal characteristics,adjacent strucure).The results were analysed with X2 test,p<0.05 were defined as threshold for statistical differences and p<0.05 were significant differences.ResuIt:The male and female ratio of benign GGO(19:12) were higher than that of maligant(23:26),but no difference were found(p>0.05).The incidence of round shape,irregular, lobulation,speculation,spine-like process,well-defined interface,ill-defined interface,pleural indentationsign and blood vesselclueter sign of benign cases (n=9,25,1,10,3,14,17,5,13)were different from those of maligant cases(n= 43,6,30,26,28,43,6,25,42),x2 vlaue(32.22,29.14,4.57,20.03,16.82,11.47,20.24,p<0.05).No differences were found in the incidence of vacuole sign,honey-combing and air bronchograms between benign and maligant cases.x2 value (1.77,0.07,0.77, p>0.05).fGGO were divided into pure ground-opacity (pGGO)and mixed ground-opacity(mGGO) by including solid ingredient.pGGO group were 43 including maligant 17 and begnign 26.mGGO group were 40 including maligant 32 and benign 8.There were defference between two group(x2 value15.42,p<0.05).Conclusion:Ground glass opacity pulmonary lesions of benign and malignant imaging findings of certain features.Lesion size fGGO diagnosis of benign and malignant lesions of limited value;lesion round the edge of signs(lobulation,spicule sign, spine-like protrusions),lesion-lung interface clear, adjacent structures (pleural indentation, vascular convergence sign)for fGGO benign and malignant differentiation has important value, which is the basis of pathology of malignant lesions in the corresponding relationship exists;vacuole sign,thin air bronchogram is fGGO important signs of malignant lesions;fGGO lesions,the proportion of ground-glass density in the quantitative sub-components type contribute to the identify-cation of benign and malignant.