Relations Between Hypertension And Stanford Type B Aortic Dissection Of Chinese People Relations Among Morphological Factors Of The Three Branches Above The Aortic Arch And Stanford Type B Aortic Dissection Of Chinese People

Objective:To probe into the risk factors of Stanford Type B Aortic Dissection through a case-control study, including hypertension and several morphological statistics of the brachiocephalic artery, the left common carotid artery and the left subclavian artery. Evaluate their roles in the occurrence of Stanford Type B Aortic Dissection and provide relevant prevention and therapy.Methods:(1) The case group:from December 2009 to August 2010, the cases were diagnosed with Stanford Type B Aortic Dissection through CTA in Zhongshan Hospital, Fudan University. Three morphological parameters were got measured by enhanced CT. A:The distance from the root part of the brachiocephalic artery to the root of the left common carotid artery. B:The distance from the root of the left common carotid artery to the root of the left subclavian artery. C:The distance from the coronary artery to the root part of the brachiocephalic artery. (2) The control group:the patients at the same time, who were suffering from the subclavian artery occlusion or stenosis, pulmonary hamartoma, pulmonary cancer. Those patients all underwent enhanced CT scan during their hospitalization.(3) The Sampling:according to the selection criterias of the cases and the controls, selecting all Stanford Type B aortic dissection patients as the cases, and the controls were selected from non-Stanford Type B aortic dissection through random sample.Results:212 cases in total were involved in this research, outputs:(1) hypertension was the main risk factor of Stanford Type B aortic dissection. There was significant discrepancy in the proportion of patients having hypertension between cases and controls, with its OR=11.98. (2) The distance from the root part of the brachiocephalic artery to the root of the left common carotid artery had no statistical discrepancy between the cases and controls, with P=0.33. However, in proportion of patients who had a common origin of the brachiocephalic artery and left common carotid artery, there was significant discrepancy between cases and controls, with P=0.0001. (3) The distance from the root of the left common carotid artery to the root of the left subclavian artery had no statistical discrepancy between the cases and controls, with P=0.57. (4) The distance from the coronary artery to the root part of the brachiocephalic artery had no statistical discrepancy between the cases and controls, with P=0.44.Conclusion:(1)Hypertension was the main risk factor of Stanford Type B aortic dissection, therefore the control of hypertension is one of effective measures in reducing the occurrence of aortic dissection. (2) In patients had a common origin of the brachiocephalic artery and left common carotid artery, there was a higher possibility of Stanford Type B aortic dissection. (3) The distance from the root of the left common carotid artery to the root of the left subclavian artery had no relation with the occurrence of Stanford Type B aortic dissection. (4) The distance from the coronary artery to the root part of the brachiocephalic artery had no relation with the occurrence of Stanford Type B aortic dissection.