| Background:currently, obesity patients are growing all over the world, obesity is becoming a global epidemic disease. This is a serious threat to human life and health and quality of life. With the increasing incidence of obesity, people urgently need effective and safe treatments. Because of the urgency and importance in the treatment of morbid obesity and restrictive effect of medical treatment, with the development of laparoscopic surgery, laparoscopic surgery for morbid obesity becomes more popular, in recent years the number of surgical express double. Laparoscopic adjustable gastric band (LAGB)is now in the application of more than 40 countries around the world, there are hundreds of thousands of obesity patients accepted the LAGB, which is the standard weight loss surgery in Europe and Australia. Literature reports at home and abroad have been contradictory. Some studies suggest that LAGB may lead to long-term weight loss and low reoperation rate; others observed that after several years there appears a declining efficiency and an increasing chance of long-term complications.Objective The purpose of this study is to analysis a large amounts of long-term follow-up outcome of obesity patients after LAGB in domestic. We find out the relief of complications in obesity patients after LAGB, find out how the weight loss and find out the complications after LAGB.We evaluate the long-term effective, feasibility and relation factors.Method There are 226 patients in domestic underwent LAGB operation at our department from June 2003 to July 2010. We compare preoperative weight and preoperative complications associated with obesity that of postoperative. In 226 cases, the longest follow-up of more than 7 years, the shortest half a year, for various reasons there are 101 cases lost to follow up, loss rate of 44.69%. There are 67male cases, for 29.65% of total cases;.159 female case, for 70.35% of the total cases. The mean age of the patients is 27.43 years, standard deviation is 8.56, median of 26 years, in all cases of the Group the minimum age is 14 years, the biggest aged 56. Span of age is up to 42 years. The weight is between 67KG and 105KG, median is 105KG,mean is 108.18KG, standard deviation is 25.70 KG. The height is between 150cm and 193cm, median is 166cm, and mean 167.73cm, standard deviations is 7.81cm. BMI is from 26.17 per cent to 61.69 per cent, the median is 36.94, mean is 38.04, standard deviation is 6.58. Results:The rate of Complication of obesity in patients underwent LAGB is up to 82.18%, only 17.82% of the patients is without any complications. The patients with fatty liver occupied the highest rates which is76.27%, followed is with high blood,50.74%.8 patients are diabetes mellitus, account for 6.25%. There are 38 patients with the other accompanying diseases, accounting for 21.84%, of which 28 cases are abnormal pituitary, a rate of 16.09% of the total cases. For obesity patients with hypertension, a cure rate of hypertension of 36.36% after LAGB, treatment effective for 81.81%. The rate of cure for patients with high blood sugar is 40%, treatment of effective rates of 100%.Up to now the mean weight lost 18.1 Kg, the median is 18.25 Kg, the worst weight-loss effects is for gain 0.5 Kg weight, the weight of best weight-loss patients reduce up to 60 Kg. The mean BMI index drop to 6.41 KG/m2, median is 6.58 KG/m2, the worse is to 0.16 KG/m2, the best is to reduce 23.44 KG/m2. When the patients reduced to the best effect of weight loss after LAGB, the mean best weight losing was 23.16 Kg, the median is 22 Kg, and weight-loss is from the worst OKg to the best 70.4Kg. The mean BMI index declined 8.19 KG/m2, median to 7.69 KG/m2, the worst effects is to reduce 0 KG/m2, the best effect is to reduce 27.5 KG/ m2.Last follow up treatment results is worse than the best follow up treatment results and this have a statistically significant (weight loss level and BMI index level corresponding to the comparison test p-value is less than 0.0001). The "effective" of lose weight is defined as the rate of weight loss in patients excessing50% of body weight in patients.The effective rate is59.82% when patients reached the lowest weight after LAGB and up to now the effective rate is 48.21%.9 patients of all,8.04%, did not show signs of weight loss after the operation.36 patients, accounted for 32.14%, weight continued decline, but the weight did not still reduce50% of extra weight; 13cases (11.61%) had reduced 50% of extra weight, but later rebound to close to original weight level; 17 cases (15.18%) had reduced 50% of extra weight, later rebound, but the lost weight still over50% of extra weight; 37 cases (33.04%) lost weight gradually, they had reduced 50% of extra weight. Patients may reach the lowest weight after 12 months of LAGB, and gradually some patient's weight is likely to rebound. And 33 cases appears complications and the rate is14.60%,17 of the 33 cases removed the band.20 cases removed the band for adverse reactions and pregnancy, the rate is 8.85%. No deaths, the mortality rate of 0%.Conclusions Obesity patients have multiple complications, after LAGB some complications such as diabetes may relief or even be cured. And the weight may loss. So far, after LAGB operation,48.22% of patients had reduced 50% of extra weight,91.96% of patients had lost weight,59.82% of patients had ever reduced 50% of extra weight, and after one year of the operation most patients'weight reached lightest, later rebound. But patients'gender, age, the BMI before operation, complications and injection numbers are not the significantly factors which may affect losing weight. The rate of the complications after LAGB operation is14.6%, 20 cases get rid of the band for adverse reactions and pregnancy, the rate is 8.85%. Sex, weight, frequency of water injection, associated disease before the operation are not significantly affection factors of complications after LAGB operation. Through statistical analysis, age is an influence factor of complications after LAGB operation, younger, higher rate of complications after LAGB operation, but this needs further research to verify in clinical. BMI index corresponds to the p-value is 0.0678.When a equal to 0.05, the effects of BMI to adverse reaction after operation has mot statistical significance, but we still believe that this has significance in the further study. Due to the restrictions of the numbers of cases and follow up time, we need more obesity patients, setting up more comparation teams, and a further detailed study for its influencing factors of bariatric surgery and losing weight such as diet, exercise, lifestyle after LAGB. In order to optimise the future use of bariatric surgery as a therapeutic modality further research is required...
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