Clinical Analysis Of 136 Cases Of Pregnancy With Bacterial Vaginal Disease

Objective: To observe the clinical manifestations and chemical examination of patients with bacterial vaginal disease 28 weeks after pregnancy in my hospital during the past two years;To analysis pregnancy outcome diversity of the pregnancy women between bacterial vaginal patients and normal pregnant women; To analysis pregnancy outcome diversity of bacterial vaginal women between patients under treatment and without treatment; To analysis correlation between pregnancy women with bacterial vaginal disease and social factors; To analysis morbidity of pregnancy with bacterial vaginal disease in different gestational age; To analysis neonatal weight and terminated pregnancy situation between pregnancy with bacterial vagina and normal pregnant women.Methods: Retrospectively analysis prenatal vaginal discharge detection result of pregnancy women who visited out patient clinic of the Chang Chun Maternity Hospital from January in 2009 to December in 2011. Patients were screened by the following standards: (1) The age range from 21 to 45,33 by average. (2) the menstrual flow was regular before pregnancy, and the last menstrual period was clear,besides the actual gestational weeks could be confirm by ultrasound detection. (3)the 28～41 weeks gestation women were informed and agreed the vaginal secretions examination. (4) the pregnancy outcome can be followed. (5) the pregnancy women with other complications were excluded in the observation,such as hypertension , placental presentation , placental abruption , superfoetation , genital malformation, fetal malformation, and also the pregnant women using antibiotic were not included. (6)The other vaginitis were excluded in the observation. (7) BV diagnosis: according to Amsel method, patients meeting three of the following four items can be diagnosed with BV. (1) the secretion is uniform and thin, often attached to the vagina wall secretion, easy to be wiped; (2) the vaginal pH > 4.5; (3) whiff test is positive; (4) clue cells ispositive. Through the statistical analysis and comparison, clarify the effect of pregnancy with bacterial vaginal disease to the pregnancy outcome,the correlation between BV and etiological factor,the incidence at different gestational weeks,the postpartum neonatal weight,and the termination of pregnancy weeks.Results: 1. 476 in 558 pregnant women in outpatient service from January in 2009 to December in 2011were enrolled into the observation, of which there were 136 cases pregnancy with bacterial vaginal(BV group) and 340 cases normal pregnancy women (control group).94 patients(94/136) in BV group manifested increased secretion, 28(28/136)showed traing flavour secretion,47 complained pruritus vulvae.Besides,the incidence rate of BV in pregnancy women(136/558)is higher than women without pregnance.2. In BV group ,19 cases(13.97%) ended up with premature delivery, 21 cases (15.44%)premature rupture of membrane,8 cases(5.88%)endometritis,6cases(4.41%) puerperal infection,4 cases(2.94%) infection of newborn. Compared with normal pregnant women group ,BV pregnant women showed significantly higerincidence(P <0.05) of premature birth, premature rupture of membrane, endometritis, puerperal infection and neonatal infection rates. 3. The BV group was divided into treatment group and without treatment group by whether the patients accepted treatment,the result showed that the BV pregnant women after treatment appeared significantly lower incidence (P < 0.05) of premature birth, premature rupture of membrane, endometritis, Tire premature rupture of membraneand neonatal infection rates than untreated BV patients. 4. The 25 year old women or youger occupy 19.12 percent,the women between 26 and 34 year old account for 66.91 percent,the 35 year old women or older take up 61.76 percent.Besides,pregnant women in the countryside(61.76%) showed significant higher incidence(P<0.05) than that in the city(38.24%).There was no significant difference(P > 0.05) between pregnant women who underwent systemic antenatal examination and those did not.5. Pregnant women with BV in 37 to 39 + 6 pregnancy weeks showed higher morbidity (30.27%), followed by 34-36+6 pregnancy weeks(28.18%). incidence rates for Different gestational age ofcomparison between groups, The difference was statistically significant(P<0.05).6. The average delivery weeks in BV group was 37.12±1.26 weeks,which is significantly lower (P<0.05)than that(38.77±1.44weeks) in normal pregnant women.7. In pregnant women with BV,the average weight of neonate was 3067±14.9 gram,while in control group the average weight of neonate was 3342±12.9 gram,The difference between the two groups had statistical significance.Conclusion: 1. Compared with normal pregnant women group ,BV pregnant women showed significantly higer incidence of premature birth, premature rupture of membrane, endometritis, puerperal infection and neonatal infection rates.2. The group BV pregnant women after treatment appeared lower incidence of premature birth, premature rupture of membrane, endometritis, puerperal infection and neonatal infection rates than untreated BV patients.3. The incidence of bacterial vaginal disease in pregnant women was correlated with age, pregnant women situation live (urban or rural), onset age, do exist, and was not related with systemic antenatal examination.4. Pregnancy with BV showed high onset rate in 37 to 39 + 6 weeks after pregnance.5.The delivery week and the average weight of neonatus in Pregnancy with BV group were less than the control group.