Clinical Analysis On Early Bacterial Infections Complications After Allogeneic Hematopoietic Stem Cell Transplantation

Objective:To analyze the clinical etiological characteristics and risk factors of early bacterial infection after allogeneic hematopoietic stem cell transplantation (HSCT). Method:To adopt investigation way to review and analyze the clinical data and risk factors of bacterial infection from 89 patients following allogeneic HSCT performed in the hematology department of the first affiliated hospital of XinJiang Medical University from January 2008 to November 2010. The risk factors include ANC count and Acute Graft versus Host Disease, (aGVHD), ANC decreased sustained time after allogeneic hematopoietic stem cell transplantation (HSCT). The data were analyzed with single-factor analysis X2 test. Results:Among 89 patiens,42 patients occurred early infection. The incidence rate of early bacterial infection was higher, which was related positively to the risk factors except for sex and age. The most common infection position of early bacterial infection was respiratory tract, gram-negative bacteria is still the most pathogen in our hematology department, secondly that is gram-positive bacteria, the last one is fungus. Conclution:The patients afert allogeneic HSCT are susceptible to early bacterial infection. To boost body, denfenses and control risk factors are effective methods to prevent early baterial infection, providing total environmental protection and useing The therapeutic effect can markly decrease the incidence of early bacterial infection.