| Background and purposeIn 1988 Reaven proposed the concept of X-syndrome, and found that insulin resistance (insulin resistance, IR) is the main features of X-syndrome. In view of X-syndrome and is closely related to a variety of metabolic diseases, such as advocated in 1997 Zimmet named X-syndrome metabolic syndrome (metabolic syndrome, MS). In 1999 the World Health Organization (WHO) working definition of MS for the first time, followed by more than 6 years to the global medical and health institutions put forward different definitions of MS. the Chinese Medical Association in 2004 also made the Chinese people's working definition of MS. These differences resulted in the definition of clinical research and academic exchanges of confusion, so in 2005 formulated a uniform definition of MS worldwide.MS is a variety of metabolic abnormalities in the pathological state of components, including:abdominal obesity or overweight, dyslipidemia (high triglyceride (TG) hyperlipidemia, and high-density lipoprotein cholesterol (HDL-C) is low), hypertension, IR and/or impaired glucose tolerance. Part of the standard also includes microalbuminuria. hyperuricemia, increased pro-inflammatory state and promote increased thrombotic state. Abnormal metabolism of these ingredients are together in the same individual, so that the risk of cardiovascular disease has increased considerably. Also MS can lead to elderly spiritual, the psychological pressure increasing and in turn can aggravate MS, thus precipitating and the state of spiritual, the psychological MS also not allow to ignore.Metabolic syndrome has become the current focus of the study at home and abroad. In China there has been reported in many parts of the epidemiological characteristics of MS and related factors, however, lack of relevant research results in the region.This study aimed to explore the old MS examination of the region's fashion trends and related factors to infer the trends in old people in MS and related factors in order to provide guidance for prevention and treatment, provide the basis for regional health policy.MethodsFrom 1 January 2007 to December 31,2009 the elderly (elder than 60 year old) in our hospital aim to body examination were entered our study. Gradient stratified sampling method is used. Total sample is 4782 cases, of which 1258 cases in 2007, 2008,1487 cases,2037 cases in 2009, Male 2731 cases,2051 cases of women, mean (72.7±15.4) years. According to the study specific medical examination form, measuring patient weight, hat height, waist circumference (waistline, WL), and calculate body mass index(body mass index, BMI). Each participation examiner is acquired to fill the anxiety self-assessment table (SAS) and depression self-assessment table (SDS). Blood pressure is detected and recorded. Blood lipid spectrum (TC, TG, HDL-C, LDL-C) and the glycolic index (FPG,2hPG) were measured by biochemical methods.SPSS 11.5 statistical software package is used to analyze data by t test, or x2 test according to the different index. Related factors were analyzed by logistic regression.Results1.Demographic data In this group were diagnosed MS 1057 patients, the incidence rate was 22.10% in the region. Male and female incidence rates were 20.80% and 23.84%, the gender difference was not statistically significant (x2=1.639, P> 0.05); in education, population origin, place of residence and the distribution of different years are not statistically significance (P> 0.05).2.Relationship with the disease MS, obesity, hypertension, hyperglycemia, and hyperlipidemia was significantly higher than the incidence of non-MS group, the difference was statistically significant (P<0.05).3.Relationship with the target MS MS, BMI, WL, SBP, DBP, TC, TG, HDL-C, LDL-C, FPG and 2hPG level of the index and non-MS group differences were statistically significant (P<0.05).4.Logistic regression The BMI, WL, SBP, DBP, TC, TG, HDL-C, LDL-C, FPG and 2hPG as the independent variable X, the incidence rate of MS as the dependent variable Y, to establish logistic regression model. The results showed that WL, SBP, DBP, TG, HDL-C, FPG, and high incidence of MS 2hPG as an independent risk factor (P<0.05). Central obesity is an independent risk factor but not BMI.5.MS group and non-MS group of anxiety and depression. Anxiety and depression in MS group is significantly higher than non-MS groups (P<0.05). Level of anxiety and depression is significantly higher in women than men with MS (P< 0.05). For non-MS group, level of anxiety and depression were no different between men and women. In male group, level of anxiety and depression are similar in MS to non-MS. However, for women, level of anxiety and depression in MS is higher significantly in non-MS. ConclusionThe examination found that the incidence of older MS 22.10%, lower than in other parts of the report. Among them, the local residents and foreign residents, women and men, education and rural and urban populations on the distribution of the incidence of MS were not significant difference. Year distribution at the point of view, from 2007 to 2009, incidence of MS was not significant difference, but displayed an increasing trend year by year, suggesting that MS prevention should be strengthened.This study showed that MS patients were 40.59% obese or overweigh,34.91% dyslipidemia, and 24.31% hypertension,21.57% glucose increased. BMI, WL, SBP, DBP, TC, TG, HDL-C, LDL-C, FPG and 2hPG were significant different between MS and non-MS group. Among them, WL, SBP, DBP, TG, HDL-C, FPG and high incidence of MS 2hPG are independent risk factors. Central obesity is an independent risk factor for MS rather than BMI. HDL-C is a protective factor for MS. HDL-C concentration is a negative correlation to MS incidence. Incidence of anxiety and depression in MS group is significantly higher than non-MS groups.In sum, there is a high incidence of MS in the elder. Level of anxiety and depression in female elder is higher than male elder. |
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