The Use Of 1540nm Fractional Phototothermolysis For The Treatment Of Atrophic Scars In Asian Skin

Purpose:Non-ablative fractional resurfacing generate microscopic columns of coagulated tissue through the epidermis and dermis to evoke a wound healing response. It has been found to be effective in treating multiple skin conditions with minimal patient discomfort and post-treatment erythema. Scars affect the entire population, causing significant distress and concern. Numerous treatment modalities are available for atrophic scar management. One of the newest trends in dermatology has been the usage of nonablative laser systems for scars. However, a 1540nm fractional photothermolysis study has not yet been performed in Chinese patients. This study aim to evaluate the efficacy and safety of 1540 nm erbium:glass fractional laser in the treatment of atrophic scars in Asian skin.Method:Twenty volunteers (15 females and 5 males, ages 17-31 years, Fitzpatrick skin typesⅢ—Ⅳ) with mild to moderate atrophic scars, such as acne scar and surgical scars, were enrolled. Scar lesions were treated with 1540 nm fractional photothermolysis (StarluxTM 1540). a series (typically 2 to 6 treatments) treatment sessions were conducted for each patient at 4 weeks intervals. Assessments included grading on a 4-point scale by two independent physicians using digital photography taken before and after the treatment and patients'satisfaction with the treatment. Side effects were evaluated as well.Results:A mild to moderate clinical improvement was seen for atrophic scars in majority of patients. Relative to baseline,6 patients had an improvement of greater than 75% in scarring,8 patients had a 51% to 75% improvement, and 1 patient had less than a 25% response to treatment. 85.0% of patients were overall satisfied with the treatment, which paralleled the physicians'assessment. After the treatment, side effects were limited to transient erythema and edema. No posttreatment pigmentary changes and other severe side effect were noted. Downtime was minimal-to-none for all subjects.Conclusion:These data illustrate treatment with the 1540 nm fractional photothermolysis laser is a safe and effective option for patients seeking reduction of atrophic scars, even in patients with Fitzpatrick Skin Types III to V. The advanced technology provides an efficient delivery of laser energy into the tissue, reducing complications and patient downtime. Continued clinical studies of further treatment are underway.