Study On Correlation Of Drainage Veins And Hemorrhage In Cerebral Arteriovenous Malforamations

OBJECTIVE:Studies in patients with cerebral arteriovenous malformations (cAVMs) have yielded contradictory results about risk factors for cerebral hemorrhage. We performed a retrospective study in a bounch of AVM patients, examined the angiographic features on drainage vein of cAVM, find out whether there are relationships between the drainage vein and brain hemorrhage.METHODS:The clinical and angiographic data of 103 patients with AVMs was retrospectively analyzed. Dural arteriovenous fistula, brain non-plexus arteriovenous fistula, cavernous malformation, and other vascular malformation were excluded. Drainage vein was divided into 3 groups (1.2 and≥3). Drainage vein pattern was defined as superficial, deep and combined:the data was managed and analyzed with SPSS software (Version 13.0; SPSS inc, Chicago, IL). A probability value of less than 0.05 was considered statistically significant in each analysis.RESULTS:In the 103 patients with AVMs.58 were male and 45 were female, age was 23.06±11.63 in average, range from 5 to 50.47 cases presented with hemorrhage and 56 were none.47 cases with one branch of drainage veins,26 with two,30 with three and more than three.57 were superficial venous drainage,20 were deep, and 26 were combined. In the nidus of AVMs,28 and 75 drainage veins were demonstrated with variceal dilatation or venous stenosis respectively. By univariate analyses, deep venous drainage was related with brain hemorrhage and other factors were independent. By calculating risk index, the risk of rupture deep venous drainage is 6.393 fold (χ2=9.386, P=0.002) than superficial and combined venous drainage.Conclusions:Deep venous drainage was demonstrated as a risk factor of rupture of AVMs.