The Bacterial Distribution And Resistance Of Sputum From Primary Hospital In Guangdong In 2010

Objective: To analyze the distribution of pathogens causing respiratory tract infection and their antimicrobial resistance in primary hospital in GuangDong in 2010. Methods: Retrospectively analyze the distribution of the isolates and the results of their drug susceptibility by using WHONET 5.5 software. Results: (1) 1293 pathogens were isolated, including 1024 Gram-negative bacteria(accounting for 79.2%), 218 Gram-positive bacteria (accounting for 16.9%) and 51 fungi(accounting for 3.9%). The top five bacteria were Pseudomonas aeruginosa,Staphylococcus aureus, Escherichia coli,Acinetobacter and Klebsiella pneumoniae. (2) Carbapenem resistance was not found in Enterobacteriaceae.The separation rate of Escherichia coli producing ESBLs was 76.9%, as well as Klebsiella pneumoniae was 50.6%. The resistance of Pseudomonas aeruginosa and Acinetobacter was significant. Pseudomonas aeruginosa resistant to imipenem was 30.9%, and Acinetobacter resistant to imipenem was 34.5%. (3) 54 isolates of MRSA were separated from Staphylococcus aureus, the ratio was 39.1%.16 isolates of MRCNS were separated from coagulase-negative staphylococcus, the ratio was 76.2%. One Teicoplanin-resistant isolate and one Linezolid-resistant isolate were detected in Staphylococcus aureus.Conclusion: Increasingly prominent bacterial resistance damand us to strengthen the surveillance of bacterial resistance, and strengthen the communication with the clinicians to explore a reasonable way of using antibiotics. This is important.