| Background: Accurate measurement of left ventricular function in clinical heart disease early diagnosis, treatment decisions, prognosis and treatment evaluation, which are important, so find a more rapid, simple and accurate measurement method is very necessary. Current clinical use of magnetic resonance, nuclear imaging, cardiac catheterization can accurate quantitative analysis left ventricular volume and systolic function, but these methods or because of expensive and time-consuming operation, or are invasive inspection and other reasons, can not be repeated inspections and follow-up, widely used in clinical practice is difficult. Echocardiography with a non-invasive, non-radioactive, mobility, check the method is simple, rapid, accurate, measurement of left ventricular volume and function with high accuracy and has been widely used in clinical, but the traditional two-dimensional echocardiography of left ventricular volume measurement based on the geometry of the heart chamber for specific assumptions, changes in ventricular shape and wall motion abnormality is difficult to make accurate assessment of ventricular volume. Real-time tri-plane echocardiography is a new technology introduced in recent years, studies have shown that the experimental measurement of rubber and in the normal and aneurysm animal model of left ventricular volume of the feasibility, accuracy and repeatability. In this study, explore feasibility, accuracy and repeatability of real-time tri-plane echocardiography measured left ventricular volume and function in the clinical.Objective: To evaluate feasibility, accuracy and repeatability of the real-time tri-plane echocardiography measurement of global left ventricular systolic function.Methods: Application of real-time tri-plane echocardiography and the biplane Simpson's method of two-dimensional echocardiography measured left ventricular end-diastolic volume (LVEDV), left ventricular end systolic volume (LVESV) and left ventricular ejection fraction (LVEF) of 30 normal subjects and 30 patients with myocardial infarction, and compare measured values with single photon emission computed tomography (SPECT). The same and different examiner application of real-time tri-plane echocardiography repeated measured and compared. Results: (1) In normal people, LVEDV measured by real-time tri-plane echocardiography and LVEDV, LVESV measured by two-dimensional echocardiography biplane Simpson's method lower than the measured value of SPECT (P <0.05); There was no significant difference between the LVESV measured by real-time tri-plane echocardiography with SPECT (P> 0.05). In patients with myocardial infarction, LVEDV, LVESV measured by real-time tri-plane echocardiography and two-dimensional echocardiography biplane Simpson's method are lower than SPECT (P <0.05); There was no significant difference among the values of LVEF measured by three ways(P> 0.05). (2) Real-time tri-plane echocardiography measured LVEDV, LVESV, and LVEF correlation with SPECT than two-dimensional echocardiography biplane Simpson's method. In normal people, real-time tri-plane echocardiography and SPECT correlation (r respectively: 0.986, 0.930, 0.868, P <0.01); two-dimensional echocardiography biplane Simpson's method and SPECT correlation (r respectively: 0.678, 0.722, 0.485, P <0.01). In patients with myocardial infarction, real-time tri-plane echocardiography and SPECT correlation (r respectively: 0.943, 0.965, 0.816, P <0.01); two-dimensional echocardiography biplane Simpson's method and SPECT correlation (r respectively: 0.896, 0.957, 0.721, P <0.01). (3) There was no significant difference between the repeated measurements by the same and different examiners with real-time tri-plane echocardiography (P> 0.05), and there was a good correlation, In normal people, intraobserver correlation (r respectively: 0.996, 0.944, 0.947, P <0.01); interobserver correlation (r respectively: 0.966, 0.964, 0.872, P <0.01). In patients with myocardial infarction, intraobserver correlation (r respectively: 0.968, 0.984, 0.883, P <0.01); interobserver correlation (r respectively: 0.948, 0.970, 0.899, P <0.01).Conclusion: Real-time tri-plane echocardiography is a fast, accurate ultrasound technology measurement of global left ventricular systolic function.
|
PDF Full Text Request