Research On Clinical Data Of Urinary Stones In North Of Zhejiang Province

ObjectiveTo compare clinical data between chemical and infrared spectrum method to detect the relationship between urinary stones and metabolism, Meanwhile, comparing clinical data among different urinary stone groups divided by their components with infrared spectrum method to provide evidence for the therapy and prevention of urinary lithiasis.MethodsAnalyzing components of 100 urinary stones with infrared spectrum method and chemical method to compare the difference between the two methods and their clinical data. At the same time compared the urinary stone analysis results of our region and other region by chemical and infrared spectrum methods.Results1. Common data:among 100 urinary stones,75 occurred in kidney,22 in ureter,2 in bladder and 1 in urethral catheter, besides,23 of the 100 stones were pure stones, the other 77 were complex ones. The stones almost located in kidney, ureter and bladder. The incidence among them was 3.4:1:0.09. The ratio between men and women was 1.4:1.2. Relationship between age and sex in lithiasis:The age ranged from 0.9 to 87 years old, the incidence of lithiasis was very low in children and eder people, while it was higher between 41 and 60 years old.3. Comparison of urine PH value, urine specific gravity, blood electroly and function of kidney:In the comparison between monohydrate calcium oxalate group and dehydrate calcium oxalate group:The age in monohydrate calcium oxalate group was younger than in dehydrate calcium oxalate group, Urine PH value in apatite group was higher than in calcium oxalate+urine acid group and calcium oxalate+apatite group, with P value 0.002 and 0.004. There was no difference in other components among those groups. The comparison in calcium oxalate group, acid group, and cystine group:The age in cystine group was younger than in calcium oxalate group and urine acid group, with P value both lower than 0.001, urine PH in urine acid and cystine group were lower than calcium oxalate group, with P value 0.038 and 0.025, Blood urea nitrogen in urine acid and cystine group were lower than that of calcium oxalate group, with P value 0.042 and 0.021. There was no difference in other components among those groups4. Comparison between chemical and infrared spectrum method:The chemical method can only detect the quality of stones while the molecular structures could not be analyzed. The pure stones were almost calcium oxalate,. apatite, urine acid or cystine while mixed stones were almost calcium oxalate+apatite or calcium oxalate+urine acid. It was difficult to analyze stones when its components were less than 15%, which led it unable to detect complicated stones such as apatite while infrared spectrum method can detect stone with their quality and quantity. The pure stones were almost calcium oxalate,urine acid and cystine while mixed stones were almost calcium oxalate+apatite, calcium oxalate+urine acid and calcium oxalat+ urine acid+apatite.5. Comparison among urine stones with infrared spectrum method:The results were similar among north of Zhejiang, Changsha and Guilin areas, The ratio in calcium stones was higher than north of Zhejiang and Changsha areas. Stones with urine acid, calcium oxalate+urine acid, apatite and calcium oxalate+ apatite in north of Zhejiang were higher than in Changsha and Guilin areas, the ratio of detection was 5% for cystine stones in north of Zhejiang area while it could not be detected in the other two areas.Conclusion1. infrared spectrum is a good method to detect urinary stones. 2. Accurate analysis of urinary stones is significant in understanding the reason, clinical therapy and precaution for the disease.3. There is difference in components between north of Zhejiang and other areas.