Changes Of Eye Accommodation On The Patients With Type 2 Diabetes Mellitus When Blood Glucose Raises

ObjectiveTo investigate the changes of eye accommodation on patients with type 2 diabetes mellitus when blood glucose raises.MethodsAfter informed consent, patients without obvious abnormality in fundus and anterior segments of eyes went on an ametropia examination. They were firstly diagnosed as type 2 diabetes mellitus (T2DM) in the Endocrine Clinic of the First Affiliated Hospital of China Medical University, aged from 30 to 40 years, whose fasting plasma glucose≥13.0mmol/L, and weren't intervened by treatment. In the premise of corrected vision, the accommodative amplitude and positive or negative relative accommodation of the stemma were tested, the binocular accommodative lags were examined, and accommodative flexibilities of both the stemma and the binoculus were respectively determined. After that, above data were contrasted to the relevant accommodative parameters from medical centre people of the First Affiliated Hospital of China Medical University, who were at the same age and with fasting plasma glucose level less than 6.0 mmol/L. Their accommodative parameters were tested bilaterally. SPSS 13.0 software was used for the statistical analysis.ResultsFirstly, mean value of absolute accommodation amplitude in T2DM group was (4.94±1.28)D, was significantly less than that of the control group((6.60±1.54)D, P< 0.05). Secondly, mean value of positive relative accommodation in T2DM group was (-1.27±0.33)D, which had statistically significance compared to that in the control group was (-2.41±0.53)D, (P< 0.05). Thirdly, no statistically significance of mean value of negative relative accommodation was found between the T2DM group ((+2.27±0.42)D) and the control group ((+2.29±0.49)D, P> 0.05). Fourthly, mean value of adjustment lag in T2DM group was (+0.59±0.08)D, while in the control group was (+0.62±0.09) D, with no statistically significance between the two groups (P> 0.05). Fifthly, mean value of accommodative flexibilities in T2DM group of the right eye, the left eye and the binoculus were separately (2.4±0.73) cpm, (2.57±0.67) cpm, and. (2.31±0.53) cpm, which were obviously lower than those in the control group which were (11.70±1.99) cpm, (11.42±1.89)cpm, and (8.69±2.08) cpm individually (P < 0.05).ConclusionsThe changes of eye accommodations in patients with T2DM during glucose elevating are concluded in following aspects:the accommodative amplitude, positive relative accommodation, and adjustable flexibility of the stemma or binoculus all decline but with no differences in the negative relative accommodation and binocular accommodative lag.