| Research purposeFor IVF pregnancies in early embryonic - ET patients and development for lost generally, the patient clinical pregnancy serum endocrine level, endometrial situation and for eggs observation, embryonic situation and other related material analysis, to find the effect early embryonic lost cycle in IVF happened to instruct the related factors, clinical improvement IVF - ET ending.Material and methodRetrospectie analysis from 1 January 2008 in November 2010 beginning to check in guangxi medical university first affiliated hospital reproductive medicine center line IVF - ET 202 cycle. Which occur early embryonic lost 101 cycle for the continued development of pregnancy for clinical pregnancy 101 cycle for the control group.All of the patients using corpus luteum medium-term long scheme falling tone. Gonadotropin (guide) choose fruit Serono Finn (Switzerland on promoting company), and urine gonadal hormone (zhuhai pharmaceutical) method. Regularly in the B inverted monitoring, when follicular 18MM follicular greater than 2 - more than three, injection, and in HCG10000Iu HCG injection 34-36 hours after take eggs. According to the man sperm insemination by IVF, ICSI insemination or IVF + ICSI fertilization. For all patients with eggs and embryos ShouJingLv growth situation, and carries on the observation on the third day after take eggs (D3) transplantation, the outpatient service for patients pregnancy situation follow-up. Track record and comparative analysis of two groups of patients for clinical characteristics, hormone levels, endometrial and quality of eggs and embryos.13.0 software SPSS statistical selection, data processing data with mean and standard deviation (and S) and percentage (%) said. Statistical methods single factor analysis choice 2 Independent Tests errors; RXC column league table a chi-square test. Adopt unconditional Logistic regression analysis, more factors analysis. Asher bilateral inspection, P < 0.05 significant differenceresults1. The single factor analysisComparison between the two groups the man age, abortion,infertility fixed number of year, natural number based sinus follicular frequency, abortion, number of basic E2 value, basic FSH value, basic LH value, FSH/LH ratio, BMI, all of the index of the comparative differences are not statistically significant (P > 0.05). But her age, height, body weight and biochemical pregnancy than control group, comparative differences have high statistical significance (P < 0.05)Between the two groups diagnosis, infertility cause infertility, presence of merger endometriosis, whether merger PCOS, semen source, preoperative semen parameters (see WHO provides diagnostic criteria and normal sperm abnormalities hierarchical), above the than comparative differences are indicators was not statistically significant (P > 0.05)Comparison between the two groups, starting dose guide guide use total dose, guide days, guide start-up sinus shape, Numbers of follicles HCG day E2, P, LH value, HCG day intima thickness, take the eggs, above, intima thickness comparison of each index difference were not statistically significant (P > 0.05)Comparison between the two groups, take eggs, lab insemination intimal form the composition of each index more than than compare difference was statistically significant (P > 0.05). But ET day lining form, between the two groups, the constituent ratios of statistically significant (P < 0.05).Between the two groups egg number of embryos by number, transplantation, high grade embryonic rate, work rate, the number of embryos, transgene of optimal embryo rate, embryos frozen rate comparative differences were not statistically significant (P > 0.05)2. Multi-factor analysisThe single factor analysis of factors (the woman have difference age, height, body weight, ET day lining form) for many factor analysis method, the Forward LR, the results show that the woman, age, take three eggs, is causing biochemical linear lining negative clinical pregnancy after pregnancy independent factors. The multi-factor model test, the result was statistically significant.conclusion1. The woman's age and IVF cycles of biochemical negative happened after pregnancy clinical pregnancy, the greater the relevant and her age in biochemical pregnancy termination of pregnancy, consider the higher risk with the woman older eggs quality poorer related.2. Endometrial form and IVF cycles of biochemical negatie clinical pregnancy after pregnancy occurs with relations, take three linear intima eggs, biochemical, pregnancy ended in patients with lower chance of pregnancy happened after pregnancy, consider biochemical negative clinical pregnancy tolerance of the occurrence and the endometrium were sex related.3. Height, weight may affect IVF cycles biochemical after pregnancy clinical pregnancy for obese patients, negative happened in IVF cycles ago advised its weight loss will help to improve the pregnancy outcome.
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