Follow-Up Analysis Of Percutaneous Transluminal Septal Myocardial Ablation And Pacemaker Treatment On Hypertrophic Cardiomyopathy

Objective: The purpose of this study is to summarize the clinical experience and the effectiveness of percutaneous transluminal septal myocardial ablation and pacemaker treatment for hypertrophic cardiomyopathy.Methods: Retrospective analysis was conducted to the clinical data of 5 patients with HCM hospitalized in our institute from november,2002to Apirl, 2010 who received percutaneous transluminal septal myocardial ablation and pacemaker treatment. All patients accepted cardiac resynchronization therapy and followed up after the operation. They all received routine 12-lead electrocardiogram, heart X-ray, echocardiography, 6 Minutes Walking Test , clinical cardiac function evaluation and pacemakers'parameter before and after the operation. Then we make a statistical analysis of the data. Results: 5 patients in the longest follow-up time is 9 years and the shorte- st is 2 years ,left ventricular outflow tract pressure gradient decreased signific- antly after treatment, Echocardiography shows diameter of the atrioventricular reduced, interventricular septum and left ventricular posterior wall became thinner, left ventricular ejection fraction was increasing, mitral back flow red- uced, left ventricular outflow tract widening, cardiothoracic ratio decreased , the quality of life and activity tolerance increased significantly.Conclusions: Percutaneous transluminal septal myocardial ablation and pacemaker treatment can improve cardiac function in patients with hypertrop- hic obstructive cardiomyopathy, improve the quality of life of the patients and decrease readmission rate.