Study On Relativity Between Common Patterns Of Internal Injury Cough In Infant And Chronomedicine (Circadian Rhythm)

Object:Study the relationship between common patterns of internal damage cough and the circadian rhythm in infantile by investigating the regulation of the attack and aggravation of the cough with the circadian rhythm as to provide better guidance of the clinical treatment.Methods:The objectives of the study are 271 patients from the out-patient pediatric department of the affiliated hospital of Chengdu University of TCM during December 2008 to September 2009. All the patients fit the including criteria and definitude the pattern by filling in the questionnaires. After the collation of the results, analyzed the dada with SPSS 16.0 software and got the conclusion.Results:1) Among the 271 infants, the most common pattern of TCM is phlegm-heat congesting the lung, followed by food accumulation, intense lung heat and yin deficiency and the patterns of phlegm-damp obstructing lung and qi deficiency are less common. The patterns of phlegm-heat congesting the lung and food accumulation often occurred before dawn and in the morning while the patterns of phlegm-heat congesting the lung and intense lung heat are more common before noon, and the pattern of yin deficiency happened more afternoon, at dusk and at night.2) The comparison of the incidence of all patterns at different time points showed that phlegm-heat congesting the lung and food accumulation before dawn is food accumulation is more common (P<0.01); The comparison of the incidence of phlegm-heat congesting the lung and food accumulation in the morning is phlegm-heat congesting the lung is more common (P<0.01); The comparison of the incidence of phlegm-heat congesting the lung and intense lung heat before noon is intense lung heat is more common (P<0.01); The comparison of the incidence of phlegm-heat congesting the lung and yin deficiency after noon is yin deficiency is more common (P<0.01); The comparison of the incidence of phlegm-heat congesting the lung, food accumulation and yin deficiency at dusk is yin deficiency is more common (P<0.01); The comparison of the incidence of phlegm-heat congesting the lung, food accumulation and yin deficiency at night showed that yin deficiency is more common (P<0.01); The comparison of the incidence of yin deficiency at different time points showed that there is no statistical significance of the yin deficiency pattern after noon, at dusk and at night (P> 0.05)Conclusion:1) The most common pattern of the internal damage cough in infantile is phlegm-heat congesting the lung, followed by food accumulation, intense lung heat and yin deficiency while the patterns of phlegm-damp obstructing lung and qi deficiency are relatively rare.2) There is correlation between internal damage cough and the circadian rhythm infantile; before dawn the pattern of food accumulation is more common, in the morning the pattern of phlegm-heat congesting the lung is more common, before noon the pattern of intense lung heat is more common and the pattern of yin deficiency happened more after noon, at dusk and at night.