Study On Changes Of Expression Of AFPmRNA And GPC-3mRNA In Human Hepatocellular Carcinoma After Oral Pingtiaoyin Therapy

Objective:To observe the changes of AFPmRNA,GPC-3mRNA,liver function,white cell and exist quality of primary hepatic cancer sufferers before and after supplying PingTiaoYin,To probe the clinic curative effect on supplying PingTiaoYin.Methods:60 primary hepatic cancer sufferers,randomized divided into test group 30 cases(PingTiaoYin) and contrast group 30 cases(huachansu),all of which were applied general treatments,the cause of treatment were two weeks. Mensurate the changes of AFPmRNA,GPC-3mRNA,liver's function,white cell and exist quality of sufferers before and after supplying PingTiaoYin.Results: 1)The expression of AFPmRNA and GPC-3mRNA were markedly decreased after treatment.There was no significant difference between the two groups in decreased the expression of AFPmRNA. 2)There was no marked liver function difference between the two groups。3)There were no significant differences on KPS points in the two groups。Conmclusion: Pingtiaoyin can effectively suppress the expression of AFPmRNA and GPC-3mRNA in human HCC peripheral blood,improve the immunity and exist quality.