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The Study Of The Serum β-HCG Changes In Ectopic Pregnancy Drug Therapy Protocols For Deferent Syndroms

Posted on:2011-11-01Degree:MasterType:Thesis
Country:ChinaCandidate:L JiangFull Text:PDF
GTID:2144360305963063Subject:TCM gynecology
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ObjectiveTo investigate the serumβ-HCG level curves, ectopic pregnancy syndromes, drug therapy protocols relationship between.MethodChinese medicine or/and western medicine were applied according to treatment table to treat ectopic pregnancy. And eath test of serumβ-HCG before or after treatment were recorded.245 patients of ectopic pregnancy who received the success of drug therapy in The First Affiliated Hospital of Guangzhou University of Chinese Medicine from January 2006 to December 2009 were retrospecively analyzed about their drug therapy protocols, ectopic pregnancy syndromes and serumβ-HCG level curves.ResultsIt is an indicator that the time of serumβ-HCG dropped to 50% and 90% to compare two treatment programs and two syndromes. We could know the follows. First of all, the time of bloodβ-HCG of two syndromes decreased by 50% after the treatment of Chinese medicine was shorter than it after the treatment of the combined Chinese and western medicine (P<0.05), but the time of the serumβ-HCG decreased by 90% after two treatment programs was no significant difference (P>0.05); Second, there was no significant difference that the time of the serumβ-HCG of two syndromes decreased by 50% or 90% after the two drug therapy protocols (P>0.05); third, first review bloodβ-HCG after the treatment made changes in two types:it is up-type which bloodβ-HCG was less than initial serumβ-HCG, and, it is down-type which bloodβ-HCG was more. However, it is the overall trend to reduce. Campared the two treatment programs, the rate of the up-type of the combined Chinese and western medicine treatment was higher than chinese medicine treatment. Campared the two different syndromes, there was no significant difference in up-type. In the cases of successful treatment which serumβ-HCG of next day is greater than the initialβ-HCG (up-type), the time of the serumβ-HCG decreased by 50% or 90% was longer than the cases in the down-type.ConclusionAccording to diagnosis, disease stage, and Syndromes and conditions affecting factors total score of drug use conservative treatment of ectopic pregnancy:An initial value of serumβ-HCG> 6000 IU/L drug treatment cycle is long, so conservative treatment is generally not the drug of choice; treatment initial serumβ-HCG concentration (smaller than 6000IU/L) had no effect on serumβafter treatment-HCG concentration rate of decline, according to impact factor of the total score of illness choose different drug treatment programs;2, the first review after treatment of bloodβ-HCG change the type of treatment, the combination treatment increased in Western type more, upward-type cases longer treatment, medication (particularly the use of mifepristone) for the first time review of bloodβ-HCG value higher than the initial concentration of prompt treatment time is long;3 serumβ-HCG value has dropped 50% of the time and treatment programs related to Chinese medicine treatment of bloodβ-HCG value of a 50% shorter, but has nothing to do with the syndrome, independent of the initial concentration, and serumβ-HCG values 90% decline in time and evidence-based treatment programs and are independent of initial concentration, by using traditional Chinese medicine treatment table than to use cases and western medicine in cases of bloodβ-HCG concentration in early fall faster, but later no significant difference, it still can not believe that Chinese medicine has a good effect; 4 Different Types of ectopic pregnancy after treatment of bloodβ-HCG concentration was no significant difference in ectopic pregnancy with the traditional Chinese medicine diagnosis and treatment, prescription card with the addition and subtraction should be relevant to the clinical treatment of ectopic pregnancy should Differential Treatment of Chinese medicine;5 In the course of treatment, bloodβ-HCG rise may appear modest further decline, the increase is less than 10%, stable disease if the patient can be given to observation, can be reviewed again 2 to 3 days after the preparation of serumβ-HCG Next treatment programs, do not change too fast or blind treatment;6 conservative medical treatment decreased bloodβ-HCG, the average time for 90% of 12.75±7.03 days after treatment,10 to 11 days after the fall of bloodβ-HCG concentration was not obvious, can enhance the intensity Chinese Traditional, After 2 weeks Weekly review of bloodβ-HCG, until the negative, to reduce the cost of treatment.
Keywords/Search Tags:words Ectopic pregnancy, Serumβ-HCG, therapy, Chinese medicine, Mifepristone, Curve
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