| ObjectiveDiscuss the clinical efficacy by comprehensive intervention of Chinese medicine to sub-health insomnia, to provide theoretical support and post-scientific basis to its further clinical applications and development.Research MethodsWe collected 102 volunteers met the sub-health insomnia in the outpatient of Guangdong Provincial Hospital from July 2008 to October 2009, which were divided into two groups by Center random,52 people in the experimental group, 50 people in the control group. Experimental Group:sleep hygiene instruction +balance acupuncture (insomnia points, chest pain points, shoulder pain points)+Chinese herbal drug (Bupleurum chinense and fossil fragment and shellfish decoction); control group:sleep hygiene instruction+minor acupuncture (insomnia points, chest pain points, shoulder pain points)+ placebo. Treatment:28 days. Acupuncture once a week; Drugs once a week, each volume includes the following seven days, four times in all. After the end of intervention, follow up once in the 28±3 day. Observation Scales include: Pittsburgh Sleep Quality Index questionnaire (PSQI), Insomnia Severity Index Scale (ISI), Self-rating Anxiety Scale (SAS), Self-rating Depression Scale (SDS), the amount the World Health Organization Quality of Life Form (WHOQOL-BREF), Chinese constitution scale, quantified by comparison points. Even numbers of each group were arranged by polysomnography (PSG) voluntarily. To establish a database includes the contents of the observe tables with Epidata3.1a, statistical analysis with SPSS13.0. Descriptive analysis method to calculate the frequency and composition ratio; t test for measurement data between groups, count data were analyzed using chi-square test between groups; compared the indicators before and after treatment differences using t-test (normal distribution) and non-parametric rank sum test. Paired t-test in PSG. Repeated measurements compared two groups before and after treatment. The index line chart describing the trend over time. Level of test is a<0.05.Results1. Subjective sleep(1) Lowered dichotomy of PSQI scores:Analysis of the composition, the 29th day observation, the test group has 27 cases effective, accounting for 51.9%, 21 cases effective in control group, accounting for 42.0%. Follow-up observation, the test group has 38 cases effective,73.1%,35 cases effective in control group, accounting for 70.0%. There were no statistically significant between groups (P>0.05).(2)Lowered quadruplicity of PSQI scores:Analysis of the composition, the 29th day observation, the experimental group:18 cases effective, accounting for 34.6%,13 cases markedly improved, accounting for 25%, healed in 1 case, accounting for 1.9%; the control group:effective in 18 cases,36%, markedly improved in 5 cases,10%, cured cases 0. Follow-up observation, compared with baseline, the experimental group has 15 cases effective,28.8%, markedly improved in 20 cases,38.5%; recovered in 4 cases,7.7%; the control group, effective in 20 cases,40%; markedly improved in 14 cases,28%; recovered in 4 cases, accounting for 8%. There were no statistically significant between groups (P>0.05).(3) Scores of all factors and the total score of PSQI:the 29th day observation, two groups of PSQI in sleep quality, sleep latency, sleep efficiency and daytime function factor scores and total score decreased, the difference was significant (P<0.05). Factor scores of the experimental group compared with the previous sleep time decreased (P<0.05). Sleep disturbance factor score of the control group was significantly lower than before, hypnotic drugs factor score was significantly higher (P<0.05). Follow-up observation, two groups of sleep quality, sleep latency, sleep time, sleep efficiency, sleep disturbance and total score were significantly lower (P<0.05). Follow-up of daytime function were significantly decreased compared with baseline in test group (P<0.05). There were no statistically significant between groups (P>0.05).(4) ISI:Compared with baseline, ISI total score in the 15th day, the 29th day and follow-up decreased significantly (P<0.05).There were no statistically significant between groups (P>0.05).2. Objective sleep:After treatment, the sleep efficiency and REM% of the control group were previous improved, which was statistically significant (P<0.05).3. Emotional Status(1) SAS:SAS total scores of two groups in the 15th day, the 29th day and follow-up compared with baseline decreased significantly (P<0.05). There were no statistically significant between groups (P>0.05).(2) SDS:in the 29th day observation, the control group improved significantly than before, the difference was statistically significant (P<0.05). Follow-up observation, the two groups were significantly improved compared with baseline, the difference was significant (P<0.05). There were no statistically significant between groups (P>0.05).4. Quality of life(1) Physical areas:in the 29th day observation, the control group improved significantly, the difference was statistically significant (P<0.05). Follow-up observation, two scores were significantly higher compared with baseline, the difference was significant (P<0.05). There were no statistically significant between groups (P>0.05).(2) Psychological areas:in the 29th day observation, the control group scores improved significantly, there was significant (P<0.05). Follow-up observation, the test group scores increased, but the control group scores decreased. There were no statistically significant between groups (P>0.05).(3) The field of environment and social and the quality of life:in the 29th day observation, the control group were improved, while the experimental group showed a drop points, though not statistically significant (P>0.05). Follow-up observation, the experimental group's scores were increased significantly (P<0.05), while the control group decreased.Conclusion1. Two groups of sub-health interventions can be significantly improved subjective sleep quality in patients with insomnia. 2. There may be some poor perception of sleep in sub-health insomnia patients.3. Anxiety and depression improve in Sub-health insomnia patients after the intervention, collaborate with insomnia symptoms.4. Index scores of quality of life in patients with Sub-health insomnia were increased after intervention, the test group is better than the control group to maintain efficacy.5.To Sub-health insomnia patients, sleep hygiene education with placebo and minor acupuncture or sleep hygiene education with balance acupuncture and decoction of Bupleurum chinense and fossil fragment and shellfish can be used.
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