The Differences Of The Blood Routine Indexes In Patients With Fatty Liver And Non-fatty Liver

ObjectiveTo investigate the differences of the blood routine indexes in patients with fatty liver and non-fatty liver.MethodObjects include adults who participated in physical examination in Shenyang between March,2008 and Dec,2008. For those with fatty liver and non-fatty liver found by ultrasonography, we mainly focus on the relationship between the fatty liver and blood routine indexes besides the use of the consultation questionnaire, physical examination and biochemistry,. The data was analyzed with spss16.0.ResultsOf the 8842 subjects, the incidence of fatty liver is 37.39%(3306) with alcoholic fatty liver 15%(1326)and non-alcoholic fatty liver22.39%(1980) respectively. Compared with the non-fatty liver group, WBC (white blood cell count), EO% (eosinophil ratio), RBC (red blood cell count), HGB (hemoglobin concentration), HCT (hematocrit determination), MCH (mean corpuscular Hb concentration), MCHC (mean corpuscular Hb concentration), RDW (red blood cell distribution width), PDW(platelet distribution width) were markedly increased (P＜0.001) in the fatty liver group; LYM% (lymphocyte ratio), MONO%(the ratio of mononuclear cells), MCV(mean corpuscular volume), P-LCR (the ratio of large platelets), MPV (mean platelet volume)were significantly increased (P<0.05); while PLT (platelet count) was significantly reduced (P<0.05);Compared with the non-alcoholic fatty liver group, RBC, HGB,HCT, MCV,MCHC were significantly increased (P<0.001); LYM%was significantly reduced (P<0.05); MCH, MONO%was significantly increased (P<0.05) in the alcoholic fatty liver group. ConclusionsCompared with the non-fatty liver group, the total number and differential count (except the percentage of neutrophils)of leukocytes in patients with fatty liver were significantly higher with a similar trend for erythroid cells (except MCHC), while the platelet count was significantly reduced. Moreover, a significant increase in erythroid cells (especially in MCV)was observed in alcoholic fatty liver group compared to the non-alcoholic fatty liver group, while no significant differences were obtained in the leukon and platelets system except a decrease in LYM%. These fully explained the significant importance of blood routine test as well as differential count for the etiological and clinical diagnosis of fatty liver.