The Short-term Outcome Of Grade â…¡ And Grade â…¢ Intraventricular Hemorrhage Of Preterms On MRI

ObjectiveCompare the short-term outcome of grade II and grade III intraventricular hemorrhage of preterms by measuring the bifrontal index on MRI and analyze the relative risk factors.MethodsWe retrospectively reviewed preterms admitted in our neonatal department from January 2008 to March 2010,100 preterms without brain injury on MRI were selected as the control group, measuring their bifrontal index; we also selected 62 preterms who have MRI scan during their first 7 days and diagnosed grade II or grade III intraventricular hemorrhage according to Papile's classification:38 cases of grade II, and 24 cases of grade III, all of them have MRI scan again before their 30 days. Compare bifrontal index and the general conditions between different groups.ResultsThe bifrontal index of control group is (0.30±0.04),and that of gradeⅡand grade III intraventricular hemorrhage groups are (0.33±0.03) and (0.35±0.08) respectively, there are significant difference between control group and gradeⅢintraventricular hemorrhage (P<0.05),but not between control group and grade II intraventricular hemorrhage group (P>0.05).When doing MRI again, the bifrontal index of grade III intraventricular hemorrhage group are significant larger than before (P<0.05), but there are no significant difference of grade II intraventricular hemorrhage. The mean birth weight,mean gestational age of grade III intraventricular hemorrhage group are significant lower than grade II intraventricular hemorrhage group, the in-hospital time is significant longer than grade II intraventricular hemorrhage group (P<0.05). There are no significant differences of the 1 minute Apgar score between grade II and grade III intraventricular hemorrhage groups (P>0.05). Mechanical ventilation and patent ductus arteriosus are risk factors to grade III intraventricular hemorrhage (P<0.05), pre-rupture of amino membrane,the delivery style and sexes make no significant differences between the two groups (P>0.05).ConclusionsThe bifrontal index can be an effective index to evaluate the short term outcome of gradeⅡand gradeⅢintraventricular hemorrhage on MRI. Incidence of adverse outcomes of grade II intraventricular hemorrhage groups is significant lower than grade III intraventricular hemorrhage group. Patent duntus arteriosus and mechanical ventilation are risk factors to grade III intraventricular hemorrhage.(P<0.05)...