Analysis Of Related Factors And Prognosis For Early Spontaneous Renal Allograft Rupture

ObjectiveSpontaneous renal allograft rupture is a relatively rare but serious complication after renal transplantation. Not only it affected renal function, but also it was more likely to endanger the life of patients. This study retrospectively analyzed the early kidney rupture-related factors and renal rupture surgery on the prognosisMethodBetween January 1,2001 and January 31,2008, renal allograft patients in our hospital,15 patients who developed spontaneous renal allograft rupture with three weeks was one group, according to rupture group to non-rupture group 1:3 selected a control group, and 46 patients were selected as another group. Logistic regression analysis of patients by sex, age, cold ischemia time, warm ischemia time, preoperative dialysis mode, acute rejection, treated by Double filtration pasmapheresis and CRRT, such factors as whether associated with the spontaneous renal rupture. Student t test comparing rupture group to control group 3 months,6 months,1 year of glomerular filtration rate (eGFR). By Kaplan-Meier analysis compared two group 1-year person survival rate and kidney survival rate. ResultsAcute rejection and treated by Double filtration plasmapheresis are associate with transplant renal rupture related (P<0.05). Glomerular filtration rate in both groups (e GFR) showed no significant difference.1-year graft survival rate of transplanted renal allograft rupture group was 86.7% and control group was 97.8%(P> 0.05), no statistical difference between the two groups. With renal allograft dysfunction as censored values:1-year graft survival rate of transplanted renal rupture group was 93.3% and control group was 97.8%(P> 0.05), the 1-year graft survival rate was no statistical difference between the two groups.1-year people survival rate of transplanted renal rupture group was 86.7% and non-rupture group was 100%(P<0.05), which was statistically significant.ConclusionSpontaneous renal allograft rupture is mainly due to acute rejection, acute rejection, and Double filtration plasmapheresis treatment associated with renal rupture. Renal allograft rupture treated by surgery has no significant impact in the glomerular filtration rate.1-year graft survival rate after renal allograft rupture group is lower than non-rupture group, but with renal dysfunction as censored values, the graft survival rate is higher than the actual graft survival. Reduce the complications after renal allograft rupture postoperative can increase the graft survival rate.