The Analysis Of Clinical Features Of Women With Polycystic Ovary Syndrome

Objective:76 patients with polycystic ovary syndrome (PCOS) and controlled-group 74 cases have been enrolled to this study , we want to discuss the clinical and biochemical characteristics of PCOS patients in our hospital ,also the risk factors which can induce the possible occurrence of PCOS .This article provide a reference that whether the standard of the Rotterdam accord with Chinese population.Methods :A retrospective study has been performed to analysis patients with PCOS between 2009- 2010 in the First Hospital of Jilin University reproductive center hospital clinic, patients with PCOS use the Rotterdam criteria for the collection. PCOS patients were 76 cases , controlled-group were 74 cases, with regular menstruation,age-matched,non-endocrine diseases.In the clinical work ,we collect their detailed history, detect biochemical features , using case-control study on the clinical characteristics to analysis biochemical markers and resigster the data to the Excel databases, compare them by using SPSS13.0 statistical analysis software for statistical analysis, normality test line between the two groups using t test. Results:1. In this study, age of PCOS patients is mainly between 20-30 year, which is consistent with foreign reports.2. In this study, the commonest clinical features of PCOS were: menstrual dysfuction 93.4% (71/76), polycystic ovaries 93.4% (71/76), LH / FSH ratio 84.2% (64/76), insulin resistance 73.7% (56/76), obesity 51.3% (39/76), family history 51.3% (39/76), hyperandrogenism 27.6% (21/76), hirsutism and (or acne) 19.7% ( 15/76).3.LH/FSH ratio is higher incidence of investigations in the PCOS group 84% (64/76).4. First-degree relatives (parents, sisters, brothers) with 26 cases of hypertension, diabetes 10 cases, male alopecia 12 cases .5.Testosterone is higher in PCOS patients obese, total T,HOMA-IR and other indicators are higher than non-obese group. OGTT test should be taken four times a line of blood, 0min +60 min +120 min +180 min.Conclusion:1. Menstrual dysfuction and polycystic ovaries are the main features in Childbearing years of PCOS patients in our hospital,hyperandrogenism,hirsutism and acne are in low incidence according to the Rotterdam criteria, PCOS patients are accord with the Rotterdam critera.2.Whether the LH/FSH ratio is regarded as one of the diagnosis criterion for PCOS requires further large sample survey. 3.Whether insulin resistance is regarded as one of the diagnosis criterion for PCOS requires further large sample survey.4. PCOS patients with obesity have more serious endocrine disorder.