| ObjectiveIn this research, according to observe and statistic the TCM symptom about the chronic renal failure (CRF) patients, we try to summarize the Characteristic and distributed rule of the TCM Syndrome of the chronic renal failure, it can provides the theory basis to improve the understanding for this disease at the aspect of Chinese medicine dialectical rules and for a better use of Chinese medicine dialectical method to improves the patient symptom with target-oriented.MethodsThis study under the "guiding principles of Chinese medicine clinical research drug (Trial)" in chronic renal failure syndrome diagnosis criteria of chronic renal failure developed clinical information questionnaire collected met the diagnostic criteria and inclusion criteria of chronic renal failure patients in general, Chinese medical information and related laboratory tests. Using a database of cases with complete data and statistical analysis. Count data using X2 test, measurement data using t test, u test, variance analysis, correlation and regression analysis. Summarized using factor analysis syndromes; using frequency distribution method of syndromes research. Chronic renal failure syndromes in patients with the characteristics and distribution of a preliminary study.Results1. The survey of 176 cases of CRF patients. Male,92 cases of 84 cases female, mean age was 58.33±18.16 years. Age 70 to 79 age group the largest proportion (22.73%); followed by 60 to 69 years and 40 to 49 age group. Men and women of all age groups was no significant differences in the distribution(P>0.05).2. The most common primary disease was chronic glomerulonephritis (38.64%), followed by diabetic nephropathy (21.59%), hypertensive nephropathy (16.48%), gouty nephropathy (9.09%), obstructive nephropathy (6.82%), polycystic kidney disease (5.68%) and hepatitis B associated glomerulonephritis (1.7%) is relatively rare.3. Using factor analysis,13 common factors, ultimately be summarized as follows: spleen and kidney qi deficiency; spleen deficiency syndrome; liver kidney yin; Qi and Yin deficiency; spleen deficiency, dampness intrinsic evidence; spleen kidney virtual, water and gas within the stop card; yin and yang deficiency, blood stasis syndrome; damp; blood stasis syndrome, etc.9. The investigation to this deficiency in patients with more common, accounting for 39.77%, followed by false is mixed, accounting for 32.39%, accounting for 27.85% positive standard; of which were the largest proportion of spleen and kidney deficiency, a total of 82 patients (46.59%), followed by the liver and kidney yin deficiency syndrome (22 cases,12.5%), deficiency of both yin and yang, at least (10 cases,5.68%). Empirical evidence of dampness marked the largest proportion (27 cases,15.34%), followed by blood stasis (26 cases,14.77%). Analysis of variance in the gender distribution of the syndrome was no significant difference (X2= 6.298, P> 0.05).4. Correlation analysis showed evidence of different CKD stages and there is a correlation between type (P<0.05, r= 0.48).5. Clinical indicators and the relationship between syndrome:analysis of variance results indicate that five of the deficiency of waiting in Ccr, Scr level of incompetence the same (P<0.05), pairwise comparison results suggest that spleen and kidney yang syndrome and deficiency of both yin and yang Ccr levels were not significantly different (P> 0.05), but the spleen and kidney qi deficiency, liver and Kidney Yin Deficiency, Spleen Qi and Yin deficiency respectively, and deficiency of both yin and yang deficiency syndrome and comparison, Ccr, Scr levels significantly difference (P<0.05). Empirical evidence in the marked wet cloud, water and gas cards, dampness, blood stasis syndrome Ccr, Scr, UA the same level of failure (P<0.05), pairwise comparisons show that the water gas card, dampness, blood stasis syndrome Ccr, Scr, UA levels and dampness syndrome were significantly different (P<0.05).Conclusion1. Chronic renal failure occurs in the elderly2. By using factor analysis,13 common factors, and finally, into the spleen and kidney qi deficiency; spleen deficiency syndrome; liver kidney yin; Qi and Yin deficiency; spleen deficiency, dampness intrinsic evidence; spleen and kidney Qi, water vapor within the stop card; yin and yang deficiency, blood stasis syndrome; damp; blood stasis syndrome 9, obtained from several physical point of view internal organs, blood, yin and yang deficiency and blood stasis syndrome of turbid damp and The basic pathology is the basis of CRF, suggesting that evil is real is the virtual chronic renal failure characteristics of the main pathogenesis, in which the virtual kidney deficiency and mainly for the spleen, marked pathological fact in both the wet product is turbid pathogenic factors, and blood stasis CRF throughout the pathological process of the pathological process of blood stasis through the CRF.3. In chronic renal failure at different stages have different characteristics:in the earlier evidence of this deficiency syndrome, or standard-based, with the decline in renal function, evidence began to emerge evil Hou, showing signs of the vacuity, the ultimate trend is more false, evil more realistic end-stage renal failure. |