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Profiles Of Cognitive Impairment In Pakinson's Disease

Posted on:2011-09-30Degree:MasterType:Thesis
Country:ChinaCandidate:L WangFull Text:PDF
GTID:2144360305458685Subject:Neurology
Abstract/Summary:PDF Full Text Request
ObjectiveCognitive impairment Parkinson's disease (PD) patients are evaluated by neuropsychological testing, so that the doctor can make rational treatment strategies by providing a theoretical basis.MethodsA cohort of 76 patients with PD was evaluated for cognition. The Montreal Cognitive Assessment (MoCA) evaluate the degree of cognitive impairment, Benton visual retention test (BVRT) test short-term visual selection memory, phonemic fluency, semantic fluency, alternating phonemic fluency, alternating semantic fluency evaluate the function of frontal lobe, Results were compared with 37 controls matched for overall age, sex and education distribution.ResultsThe Parkinson's disease MoCA scores of 22.50±4.65 was significantely lower than the control group MoCA scores of 25.26±2.274 (P<0.001), and visual-spatial and executive function (P<0.001), immediate word recall (P<0.05), Delayed recall (P< 0.001), multipie-choice tips (P<0.05), alternative semantic fluency (P<0.05) significantly lower than the controls.Conclusions1. PD patients and controls exists mainly as a cognitive visual-spatial and executive functions, immediate recall and delayed recall of the word, alternating semantic fluency damage, and phonemic fluency, sound and meaning fluency, alternating fluency, sound and meaning, naming, attention, abstract thinking, computing power, orientation ability, visual memory relative retention. Prompted PD patients with cognitive impairment that have happened.2. We believe that the MoCA provides considerably more sensitive to evaluate the mild cognitive status of patients with PD as a cognitive screening instrument.
Keywords/Search Tags:mild cognitive impairement, Parkinson's disease, neuropsychological testing
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