The Diagnostic Value Of Preoperative Biopsy In Ampullary Tumor.

PurposeTo investigate the diagnostic value of preoperative biopsy in ampullary tumor.MethodsClinical data of 53 patients with ampullary tumors who were treated in the First Affiliated Hospital of China Medical University from January 2000 to November 2009 were analyzed retrospectively.。ResultsAll of the patients were diagnosed preoperatively by duodenal endoscopy and biopsy. Among these cases,20 cases(37.7%) were diagnosed as adenocarcinoma,19 cases (35.8%) were diagnosed as high grade intraepithelial neoplasia,13 cases (24.5%) were diagnosed as low grade intraepithelial neoplasia and 1 cases (1.9%) were diagnosed as inflammatory polyp. In 53 cases of patients,47 cases (88.9%) underwent pancreaticoduodenectomy,6 cases (11.3%) underwent local tumor resection. Pathological results were as follows:adenocarcinoma in 46 cases (86.8%), carcinoid in 1 case (1.9%), adenoma with canceration in 3 cases (5.7%), adenoma with intraepithelial neoplasia in 3 cases (5.7%)。ConclusionMost of the ampullary cancers have a high degree of differentiation, so biopsy in the surface of tumor is difficult to make a correct diagnosis. Qualitative diagnosis of ampullary tumor requires not only the biopsy,but also the shape and size of the tumor. Excision biopsy should be made if necessary.