Sex Ratio In Births After D3 Embryos Transfer

Objective:To evaluate the sex ratio in births conceived with D3 embryos transfer according to grow-rate of embryos in vitro.Methods:A retrospective analysis of IVF/ICSI patients who transfer fresh embryos and frozen embryos during the period 2007.1-2008.12 in our reproductive center. In the fresh 8cell embryos group, patients transfer fresh 8cell embryos who have both 8cell and≤6cell embryos in D3.In the frozen 8cell embryos group, patients transfer frozen 8cell embryos(cell number before frozen) who have both 8cell and≤6cell embryos in the last cycle. In the frozen≤6cell embryos group, patients transfer frozen <8cell embryos(cell number before frozen) who have both 8cell and≤6cell embryos in the last cycle.Results:In the fresh 8cell embryos group, the male to female (M/F) ratio is 432 /417(50.9/49.1). In the frozen 8cell embryos group, the male to female (M/F) ratio is 83/73(53.2/46.8). In the frozen≤6cell embryos group, the male to female (M/F) ratio is 97/98(49.7/50.3).The sex ratio(M/F) in births of each group is not different from expected 1:1 ratio. No significant difference is observed in the sex ratio of infants born as a result of fresh 8cell embryos transfer, frozen 8cell embryos transfer and frozen≤6cell embryos transfer.Conclusions:Transferring fresh grow-faster embryos in D3 can not cause an altered sex ratio of infants. Sex ratio of infants born as a result of frozen 8cell embryos transfer is higher than fresh 8cell embryos transfer.However,significance is not reached because of the limited number of infants.