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Assement Of Regional Myocardial Function In Left Ventricle Wall After Myocarditis By RT-3DE And QTVI Technology

Posted on:2011-08-20Degree:MasterType:Thesis
Country:ChinaCandidate:Y L ZhangFull Text:PDF
GTID:2144360305454605Subject:Clinical Medicine
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Viral myocariditis is a parenchymal disease based on myocardial and a interstitial disease based on interstum. In clinical, it can cause sudden death, also can have no symptoms, mainly relies on clinical manifestation, laborary and instrumental examinations for a comprehensive diagnosis. In clinical, myocarditis is divided into three kinds: light type, medium type and heavy type. The prognosis based on clinical sympotom.The study before about ventricular synchrony focused on adult heart falure, studying the absence of synchony in the ventricular, between the right and left ventricular, between the atrial and the ventricular, and resynchony therapy. Myocarditis occurs on the child younger than 8 years. when the cardiac enlargement appears, the left ventricular wall motion is synchonic or not and the relation with myocarditis, there is no domestic and foreign research reports.In the past, we mainly use M-ulatrasoud, two-dimensional ultrasound and Doppler ultrasound to evaluate the wall motion regional abnormity. But these methods are limited because of the sample points and the dependence of two dimensional image. Doppler tissue imaging is a convinient and worthy way to study the movement of myocardium. Quantitative tissue velocity imaging (QTVI)can measure diffenrent places at the same time in the longitudinal direction, which has advantages in assessing the synchony in the left ventricular wall motion.Real-time three–dimensional imaging based on a two-dimensional standard view, based on this view, cutting the heart every 60°, get two view image: one is 60°, the other is 120°, this technique can manifest three views at the same time in one range cycle and the motion of myocardium, which can avoid disturbance of the electrocardiograph and rhythm, quickly access the heart movement. Not basing on the hypothesis of ventricular cavity, even when the ventricle deforms and the regional abnormity in ventricular wall motion. Because it can non-invasively, Intuitively, accurately evaluate the motion of ventricular wall, becoming a new way to quantifyly access the function of the left ventricular and the wall motion of the ventricular wall. The technique has advantage in getting images, and dislodge the disturbance of difference in range cycle variation. The mixing of QTVI and RT-3DE Can accuarately and dependently access the absence of synchony in ventricular wall, which has advantage in evaluating the synchrony.METHODS: Two groups were devided: the control group(30 case) and the myocarioditis group(30 case).Get the sixty children's QTVI image of interventricular septum, lateral wall, anterior wall, inferior wall, anterior septum, posterior wall. Every left ventriclar wall was devided into three parts. in this way, we can probe QTVI images of 18 points. we can measure the velocy of the peak of systole flow and early diastole, we also can measure the time between the beginning of QRS to the peak of the systole (Ts) flow and to the peak of early diastole flow(Te), then calculate the maximum time difference of the same region among the six wall, (Inter-?Ts and Inter-?Te) and the same wall among the three region (Intra-?Ts and Intra-?Te), the maximum time difference among the 18 regions (Max-?Ts and Max-?Ts). RESULTS: 1,Ts and Te among the six wall and the three region is not significantly different. 2, Inter-△Ts of the myocarditis group in the base part and the middle part were significantly longer than the control group, (P<0.01), in the apex part, the Inter-△Ts of the myocarditis is significantly longer than the control group(P<0.05). Inter-△Te of the myocarditis group in the middle part is longer than the control group (P<0.01), in the basal part and the apex part, Inter-△Te is also longer than the control group(P<0.05) 3, Intra-△Ts of the myocarditis in interventricular septum, antetior wall, anterior septum, interior wall were significantly longer than the control group (P<0.01), in laterior wall, intra-△Ts is significantly longer than the control group(P<0.05), in the inferior wall, there is on difference in two groups. Intra-△Te of the myocarditis in interventricular septum, antetior wall, anterior septum, interior wall, laterior wall were significantly longer than the control group (P<0.01), in the inferior wall, Intra-△Te is significantly longer than the control group (P<0.05). 4, Max△Ts, Max△Te of the myocarditis group is significantly longer than the control group (P<0.01).5,Vs, Ve of the myocarditis group is significantly lower than the control group (P<0.01).CONCLUSION: We can quickly and accurately access regional myocarditis function in left ventricle by real-time three-dimensional Echocardiography and Quantitative tissue velocy imaging.
Keywords/Search Tags:Real-time three-dimensional, Echocardiography, dyssynchrony, myocarditis
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