The Application Value Of SWI And DTI In Diffuse Axonal Injury

ObjectiveTo evaluate the usefulness value of SWI and DTI in diffuse axonal injury(DAI).Materials and Methods1 Three groups of people including 30 DAI patients,15 mild traumatic brain injury (mTBI) patients and 15 healthy volunteers (control) were examined by GE Signa EXCITEâ…¡3.0 MR scanner. All of them have no history of hypertension, diabetes mellitus and cerebral vascular disease. GRE-T2WI, SWI were performed using an eight channels head coil and the MR images were analyzed. The quantities of brain microbleeds were counted and their distributions were recorded. SPSS 11.0 statistical package and Paired-Samples t Test were used to process the data, P<0.05 means a statistical difference.2 Two groups of people (12 DAI patients and 15 healthy volunteers) were examined using GE Signa EXCITEâ…¡3.0 MR scanner with an eight channels head coil. All of the people have no history of hypertension, diabetes mellitus and cerebral vascular disease. DTI (b=1000s/mm2) were performed and all the data were conducted by Functool 3.2 software on GE ADW4.2 workstation. FA values were measured on FA maps. The ROIs including bilateral frontal lobes, bilateral parietal lobes, the thalamus, genu of the corpus callosum, body of the corpus callosum, splenium of the corpus callosum, bilateral genu of the internal capsule, bilateral posterior limbs of the internal capsule, the brain stem. SPSS 11.0 statistical package was used to process the data, Independent-Samples T Test was selected. P<0.05 means a statistically significant difference.Results1.1 In DAI group, SWI detected more microbleeds than GRE-T2WI (P<0.001)1.2 The microbleeds that SWI and GRE-T2WI detected mainly distributed in the frontal lobes, temporal lobes and the corpus callosum.1.3 No microbleeds was detected in the mTBI group and control group.2 Compared with the control group, The FA values of all ROIs in the DAI group were much lower.Conclusion1. SWI could show microbleeds in DAI patients clearly, it was more sensitive than conventional MRI and GRE-T2WI.2. The hemorrhagic lesions in DAI patients mainly distributed in the frontal lobes, followed by the temporal lobes and the corpus callosum.3. Significant decrease of FA value could be detected on DTI in all DAI patients. It was very useful for the diagnosis of DAI.