Results Of Montelukast Combine With Seretide For Patients With Cough Variant Asthma

Objective:To compare the efficiency of Seretide plus Montelukast and Seretide only and Montelukast only on patients with cough variant asthma (CVA).Patients and methods:(1) General condition of the patients:60 patients with definite diagnosed of CVA admitted into Shandong Provincial Hospital from October 2008 to November 2009 were enrolled into our study, including 26 males and 34 females,(2) Clinical treatment:Sixty patients with CVA were randomly divided into three groups treated with Seretide plus Montelukast and Seretide only and Montelukast for 12 weeks. The pulmonary function and clinical symptom before and after treatment were observed in three groups.Result:(1) The symptom score in the group plus Montelukast were significantly lower than that in the group Seretide only (P<0.01), and the group Seretide only was significantly lower than that in the group Montelukast only (P<0.01). (2) the clinical effects of the patients(3) The forced expiratory volume in 1 second(FEV1) after treatment improvedConclusionThe clinical improvement appears more rapidly in treatment by Seretide plus Montelukast than by Seretide only, and more rapidly in treatment by Seretide only than by Montelukast only.