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A Meta-analysis Of Clinical Efficacy: Anterior Cruciate Ligament Reconstruction In The Application Of Bone-patellar Tendon-bone Versus Semitendinosus/Gracilis

Posted on:2010-01-21Degree:MasterType:Thesis
Country:ChinaCandidate:K ChenFull Text:PDF
GTID:2144360278970005Subject:Bone science
Abstract/Summary:PDF Full Text Request
Backgrouds:In the recent years, as the number of the sports and the traffic accident injuries increasing, anterior cruciate ligament injuries increase relatively. Anterior cruciate ligament injury can easily lead to instability and secondary injury , meniscus injury and even degenerative osteoarthritis after a long time , causing serious impact on daily life, so ACL reconstructions are needed. Among many operative methods, arthroscopic ACL reconstruction with its adventages in less surgery trauma and easy recovery, gradually becomes the first choice in treating ACL injury. And in the choices of anterior cruciate ligament reconstruction graft, the patellar tendon medial 1 / 3 is a good transplant material, whose both ends are the bone-tendon-bone junction with a bone - bone healing, will enhance their reliable biomechanical aspects and solid fixation. As a result, it is considered as a "gold standard" in the graft choice. Semitendinosus muscle / tendon of gracilis is following bone - patellar tendon - bone as a new ACL graft. Compared with the former, due to it's less impact on knee and reducing the incidence of secondary lesions, Semitendinosus/gracilis tendon is more conducive to postoperative rehabilitation, so that it is also used frequently. At present, two types of autograft metioned above have become the mainstream in anterior cruciate ligament reconstruction. While does one type differentiate from the other ? how to make a choice between the two? no definite conclusion is reached. A growing number of scholars carried out a large number of tests both in the postoperative knee stability objective and subjective aspects of recovery from a comparison, but the result was not so consistent and even opposite. Therefore,we need for a large number of the past clinical studies to make a systematic analysis in order to obtain more precise conclusions.Objective:1. With analysis through the reported anterior cruciate ligament reconstruction, using the conmmon postoperative evaluations of the knee functions to compare the differences of the two types of graft in ACL reconstruction. Draw more references in the choice of the graft.2. Expanding the medical research field of information science with the use of systematic evaluation of evidence-based medicine (Meta Analysis) method, so that the informatics could support medical decision-making on surgical treatments in the future.Methods:Randomized controlled trials(RCTs) and Quasi- randomized controlled trials(Quasi-RCTs) were collected from PubMed, OVID, The Cochrane Library and CNKL Evaluate the quality of all studies. Use the Review Manager 4.2 software provided by Cochrane to analysis the data.Results:10 studies met the inclusion criteria, 3 in level B, 7 in level C. The KT 1000/2000measurements[WMD=-0.91, CI95%(-2.33, 0.52), P=0.21], objective IKDC scores [RR=1.09,CI95%(0.87,1.36),P=0.47] and Lachman test [RR=1.15, CI95%(0.95, 1.40), P=0.14] there is no statistical difference between the two groups.Conclusions:According to the researches, there is no significant statistical difference between the bone - patellar tendon - bone group and Semitendinosus/Gracilis group in KT measurements, the objective IKDC score and Lachman test. It can be consequently concluded that no significant difference in improving knee stability and objective signs between the two groups, a large number of new clinical studies are still needed to verify it.
Keywords/Search Tags:anterior cruciate ligament, reconstruction, bone-patellar tendon-bone, hamstring, semitendinosus, gracilis, arthroscopy, Meta-analysis
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